Ann E Stapleton

Evid Based Med. 2013;18(3):110-111.

Urinary tract infection (UTI) is a common clinical problem that often recurs, leading to the institution of preventive measures for recurrent UTI (rUTI).[1,2] Antimicrobial prophylaxis is highly effective, but risks adverse effects and induction of resistance.[1,2] These considerations and widespread increases in antimicrobial resistance have intensified interest in alternative means of preventing UTIs, such as cranberry products. However, few well-designed clinical trials were available for analysis in the last Cochrane review of cranberry for the prevention of rUTI in 2008.[3] Wang and colleagues have re-evaluated this issue, adding several trials and an analysis of factors influencing efficacy of cranberry in preventing UTI: subject characteristics, type of cranberry product, amounts of proanthocyanidin (PACs; putative active ingredients), dose and dosing interval.

Full Text Article:  http://www.medscape.com/viewarticle/804396