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• Obesity is a growing problem worldwide and is associated with increased risk of multiple cancers. This review examines the mechanisms behind obesity-induced neoplasia.

– Richard Bambury, MD

ABSTRACT

Obesity is among the fastest growing diseases worldwide; treatment is inadequate and associated disorders, including gastrointestinal cancers, have high morbidity and mortality. An increased understanding of the mechanisms of obesity-induced carcinogenesis is required to develop methods to prevent or treat these cancers. We review the mechanisms of obesity-associated colorectal, esophageal, gastric, and pancreatic cancers and potential treatment strategies.

Full Text for Paid Subscribers:  https://www.dropbox.com/s/2bn057ab78n371e/Mechanisms%20of%20Obesity-Induced%20Gastrointestinal%20Neoplasia%20Gastroenterology%202014.pdf.