Oral Oncol 2014 Jan 02;[EPub Ahead of Print], W Wang, Y Yang, W Zhang, W Wu Research
January 08, 2014
TAKE-HOME MESSAGE
- This meta-analysis of 14 studies and 4675 oral cancer cases found that green tea consumption was associated with a 20% reduction in relative risk of developing oral cancer. The consumption of black tea was not associated with a statistically significant reduction in risk.
- The analysis suggests that green tea may have a protective effect against development of oral cancer.
ABSTRACT
OBJECTIVES
Epidemiological studies evaluating the association of tea consumption and the risk of oral cancer risk have produced inconsistent results. Thus, we conducted a meta-analysis to assess the relationship between tea consumption and oral cancer risk.
METHODS
Pertinent studies were identified by a search in PubMed, Web of Knowledge and Wan Fang Med Online. The fixed or random effect model was used based on heterogeneity test. Publication bias was estimated using Egger’s regression asymmetry test.
RESULTS
Finally, 14 articles with 19 studies comprising 4675 oral cancer cases were included in this meta-analysis. The relative risk (95% confidence interval) of oral cancer for the highest versus the lowest category of tea consumption was 0.853 (0.779–0.934), and the association was significant between oral cancer risk and green tea consumption [0.798 (0.673–0.947)] but not in the black tea consumption [0.953 (0.792–1.146)]. The associations were also significant in Asian and Caucasian.
CONCLUSIONS
Our analysis indicated that tea consumption may have a protective effect on oral cancer, especially in green tea consumption.
Oral Oncology
Association of Tea Consumption and the Risk of Oral Cancer: A Meta-Analysis
Oral Oncol 2014 Jan 02;[EPub Ahead of Print], W Wang, Y Yang, W Zhang, W Wu
Full Story: http://www.practiceupdate.com/journalscan/7517
Journal Reference: http://www.oraloncology.com/article/S1368-8375(13)00802-6/abstract