Topical NSAIDs for Acute Musculoskeletal Pain

Post on March 8, 2016 by André Broussard, D.C.

March 08, 2016
JAMA : The Journal of the American Medical Association

TAKE-HOME MESSAGE

  • The authors of this clinical evidence synopsis reviewed the efficacy of topical nonsteroidal anti-inflammatory drugs (NSAIDs) for acute musculoskeletal pain caused by sprains, strains, and overuse.
  • Good pain relief was reported, particularly with gel formations and some patches without an increase in local skin reactions and with few reported systemic side effects.

Abstract

CLINICAL QUESTION

Are topical nonsteroidal anti-inflammatory drugs (NSAIDs) associated with reduced pain intensity in acute musculoskeletal conditions, but without increased adverse events?

BOTTOM LINE

When treating musculoskeletal conditions such as sprains, strains, and contusions, topical NSAIDs are associated with greater pain relief, but are not associated with an increase in adverse events compared with placebo.

Story Source

Journal Reference

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