BMJ
Rai SK, et al.
This trial is formulated in order to analyze the correlation between the Dietary Approaches to Stop Hypertension (DASH) and Western diets with the risk of gout in men. The DASH diet appears to be linked with a lower risk of gout. Its impact on lowering uric acid levels in patients with hyperuricemia displays a reduced risk of gout. On the other hand, the Western diet links with a greater risk of gout. In conclusion, DASH diet presents as a valuable preventive dietary strategy, for men at risk of gout
Methods
- This study was a prospective cohort research.
- It took place at The Health Professionals Follow-up Study.
- The recruitment consisted of 44444 men, with no history of gout at baseline.
- With the aid of validated food frequency questionnaires, each member was assigned a DASH dietary pattern score (based on high intake of fruits, vegetables, nuts and legumes, low fat dairy products, and whole grains, and low intake of sodium, sweetened beverages, and red and processed meats) and a Western dietary pattern score (based on high intake of red and processed meats, French fries, refined grains, sweets, and desserts).
- The main measure was set as the risk of incident gout, meeting the preliminary American College of Rheumatology survey criteria for gout, adjusting for potential confounders: Age, body mass index, hypertension, diuretic use, and alcohol intake.
Results
- During 26 years of follow-up, 1731 confirmed cases of incident gout were reported.
- A higher DASH dietary pattern score correlated with a lower risk for gout (adjusted relative risk for extreme fifths 0.68, 95% confidence interval 0.57 to 0.80, P value for trend <0.001).
- On the other hand, a higher Western dietary pattern score exhibited a correlation with an increased risk for gout (1.42, 1.16 to 1.74, P=0.005).