Reference: “Clinical effects of diet supplementation with DHA in pediatric patients suffering from cystic fibrosis,” Leggieri E, De Biase RV, et al, Minerva Pediatr, 2013 Aug; 65(4): 389-98. (Address: Centro Fibrosi Cistica Regione Lazio, Sapienza University, Rome, Italy. E-mail: emanuela.leggieri@gmail.com ).

Summary: In a study involving pediatric patients with cystic fibrosis, supplementation with the omega-3 fatty acid, DHA, for a period of 6 months, was found to be associated with improvements in clinical condition of patients, as well as reductions in pulmonary and intestinal inflammation. One g/10 kg/d was adminstered for the first month, followed by 250 mg/10 kg/d for the following 5 months. Results found reductions in IL-8, TNF-alpha in serum, and calprotectin in stools, as well as improvements in auxometric parameters and clinical condition. The authors conclude that DHA may have beneficial effects in pediatric patients with CF.

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