Dr. Wayne Sodano
DC, DABCI, DACBN, CFMP, ND
(Article adapted from College of Integrative Medicine Module 27 – Dermatology and Periodontal Disease)
Psoriasis is a chronic disease that affects 2-3 % of the world’s population and between 2-4 % of the U.S. population. “Psoriasis is characterized by hyperproliferation and abnormal differentiation of epidermal keratinocytes, lymphocyte infiltration consisting mostly of T lymphocytes, and various endothelial vascular changes in the dermal layer, such as angiogenesis, dilation, and high endothelial venule formation. The proliferative cell population is approximately doubled in psoriasis, whereas the cell cycle
is more than 8 times shorter (36 versus 311 hours), and daily production of keratinocytes in psoriatic lesions is approximately 28 times greater than that in normal epidermis.”