Vitamin C Protects Kidneys Against Angiography Contrast

IMNG Medical Media, 2013 Aug 28, S Worcester
Ascorbic acid may protect against contrast-induced-acute kidney injury in patients undergoing coronary angiography, a meta-analysis of nine randomized controlled trials has shown.

The overall incidence of contrast-induced acute kidney injury (CI-AKI) among 740 patients who received ascorbic acid and who were included in the final analysis was 9.6%, compared with 16.8% in 796 patients who received placebo or an alternative pharmacologic treatment, Dr. Umar Sadat of Cambridge (England) University Hospitals NHS Foundation Trust, and colleagues reported.

“In the pooled analysis using random effects model, patients receiving ascorbic acid had 33% less risk of CI-AKI compared to the control group (risk ratio, 0.672),” a statistically significant difference, the investigators wrote.

The findings were published online Aug. 28 in the Journal of the American College of Cardiology.

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