Cancer Risk Factors

Missing link between vitamin D, prostate cancer

Date: October 22, 2014 Source: University of Colorado Denver Summary: A new study offers compelling evidence that inflammation may be the link between vitamin D and prostate cancer. Specifically, the study shows that the gene GDF-15, known to be upregulated by vitamin D, is notably absent in samples of human prostate cancer driven by inflammation. […]

Coffee consumption and mortality from all causes, cardiovascular disease, and cancer

Am J Epidemiol. 2014 Oct 15;180(8):763-75. doi: 10.1093/aje/kwu194. Epub 2014 Aug 24. Coffee consumption and mortality from all causes, cardiovascular disease, and cancer: a dose-response meta-analysis. Crippa A, Discacciati A, Larsson SC, Wolk A, Orsini N. Abstract Several studies have analyzed the relationship between coffee consumption and mortality, but the shape of the association remains […]

American Society of Clinical Oncology Position Statement on Obesity and Cancer

Jennifer A. Ligibel Journal of Clinical Oncology October 1, 2014, doi: 10.1200/JCO.2014.58.4680 © 2014 by American Society of Clinical Oncology Abstract Rates of obesity have increased significantly over the last three decades in the United States and globally. In addition to contributing to heart disease and diabetes, obesity is a major unrecognized risk factor for […]

Vitamin D Supplementation and Cancer Prevention

Thomas L. Lenz, PharmD, MA, PAPHSDisclosures Am J Lifestyle Med. 2009;3(5):365-368. ABSTRACT AND INTRODUCTION Abstract It is estimated that approximately 1 billion people worldwide have blood concentrations of vitamin D that are considered suboptimal. Much research has been conducted over the past 30 years linking low vitamin D serum concentrations to both skeletal and nonskeletal […]

Type of laxative matters for decreasing colorectal cancer risk, reported researchers in The American Journal of Gastroenterology

The American Journal of Gastroenterology , (16 September 2014) | doi:10.1038/ajg.2014.233 A Prospective Study of the Effect of Bowel Movement Frequency, Constipation, and Laxative Use on Colorectal Cancer Risk Jessica Citronberg, Elizabeth D Kantor, John D Potter and Emily White Abstract OBJECTIVES: Constipation and laxative use have been hypothesized to increase colorectal cancer (CRC) risk, […]

To Lower Your Risk of Cancer, Look to Your Waist

By: Austin Perlmutter, Medical Student, Miller School of Medicine Years of data now clearly demonstrate connections between obesity and increased risk for cancer. However, a new study published in the well-respected medical journal, The Lancet, is one of the first to examine this risk on a large scale. With over 5 million participants, the actual data is even […]

Prediabetes Associated With Increase in Cancer Risk

Story Source: Medscape Medical News Pam Harrison September 09, 2014 Prediabetes — even at lower levels of impaired fasting glucose (IFG) as defined by the American Diabetes Association (ADA) — is associated with a significant increase in cancer risk that is independent of the effects of obesity, according to the results of a large new […]

Body-mass index and risk of 22 specific cancers: a population-based cohort study of 5·24 million UK adults

The Lancet, 08/21/2014  Evidence Based Medicine Story Source Bhaskaran K, et al. – High body–mass index (BMI) predisposes to several site–specific cancers, but a large–scale systematic and detailed characterisation of patterns of risk across all common cancers adjusted for potential confounders has not previously been undertaken. Authors aimed to investigate the links between BMI and […]

Increased Intake of Vegetables, but not Fruit, Reduces Risk for Hepatocellular Carcinoma

Gastroenterology. 2014 Aug 12. pii: S0016-5085(14)01001-4. doi: 10.1053/j.gastro.2014.08.005. [Epub ahead of print] Increased Intake of Vegetables, but not Fruit, Reduces Risk for Hepatocellular Carcinoma: A Meta-analysis. Yang Y1, Zhang D2, Feng N3, Chen G4, Liu J5, Chen G6, Zhu Y5. Abstract BACKGROUND: & Aims: The anti-cancer effects of vegetables and fruit have been investigated extensively, […]

Sweetened carbonated beverage consumption and cancer risk: meta-analysis and review

Eur J Cancer Prev. 2014 Sep;23(5):481-90. doi: 10.1097/CEJ.0000000000000015. Sweetened carbonated beverage consumption and cancer risk: meta-analysis and review. Boyle P1, Koechlin A, Autier P. Abstract There is speculation on an association between sweetened, carbonated beverage consumption and cancer risk. This study aimed to examine this issue. Over 50 independent estimates of risk were available, 11 […]

Low albumin to globulin ratio associated with cancer incidence and mortality in generally healthy adults

Annals of Oncology, 08/04/2014 Clinical Article Suh B, et al. – This study suggest that low AGR is a risk factor for cancer incidence and mortality, both short–term and long–term, in a generally healthy screened population. The results of this study need to be replicated in larger studies, along with the determination of the sensitivity […]

Exposure to the sun could actually HALVE your chance of developing some forms of cancer

Exposure to the sun could actually HALVE your chance of developing some forms of cancer Sun exposure could potentially reduce the risks of ovarian, oesophageal and pancreatic cancers Not enough UV rays may cause children to develop rickets and ostemomalacia in adults Professor Neale is currently recruiting 25,000 Australians over 60 to participate in a […]

Dietary protein sources (Red Meat) in early adulthood and breast cancer incidence: prospective cohort study 

BMJ, 06/24/2014 > Evidence Based Medicine  Clinical Article Farvid MS, et al. – The aim is to investigate the association between dietary protein sources in early adulthood and risk of breast cancer. Higher red meat intake in early adulthood may be a risk factor for breast cancer, and replacing red meat with a combination of legumes, poultry, nuts […]

Ketogenic diet beats chemotherapy for almost all cancers, says Thomas Seyfried – Video

    June 20, 2014 8:26 AM MST The low-carb, high-fat ketogenic diet can replace chemotherapy and radiation for even the deadliest of cancers, said Dr. Thomas Seyfried, a leading cancer researcher and professor at Boston College. In an exclusive interview, Dr. Seyfried discussed why the ketogenic diet has not been embraced by the medical […]

Sitting down for an extra two hours increases the risk of some cancers by 10%

This effect holds even for people who do a lot of exercise when not sitting The increased risk was most notable for womb, bowel and lung cancers MailOnline By JENNY HOPE MEDICAL CORRESPONDENT PUBLISHED: 15:02 EST, 16 June 2014 | UPDATED: 12:42 EST, 17 June 2014 Stop sitting down if you want to avoid cancer, […]

Meta-Analysis of BMI and Survival in Breast Cancer Patients

Research · April 27, 2014 TAKE-HOME MESSAGE In this large meta-analysis of 82 studies evaluating the association between obesity and breast cancer survival, investigators found that increased BMI before or after breast cancer diagnosis and treatment was associated with a significant increased risk of total and breast cancer–specific mortality, in both pre- and post-menopausal women. This […]

ED Drugs Linked to Increased Melanoma Risk

Medscape Medical News Larry Hand April 10, 2014 Use of sildenafil (Viagra, Pfizer) is associated with an increased risk for melanoma, according to an article published online April 7 in JAMA Internal Medicine. Researchers caution, however, that their study does not provide sufficient evidence to change clinical recommendations for erectile dysfunction (ED) treatments. Wen-Qing Li, PhD, from the […]

New test suggests antidepressant Paxil may promote breast cancer

by Melissa Healy February 15, 2014 A team of researchers from the City of Hope in Duarte has developed a speedy way to identify drugs and chemicals that can disrupt the balance of sex hormones in human beings and influence the development and progress of diseases such as breast cancer. In a trial screening of […]

Cancers Caused by Lifestyle Behaviors: Experts Urge Action

Zosia Chustecka February 06, 2014 In launching the World Cancer Report 2014 earlier this week, the editors emphasized the need for prevention and highlighted lifestyle behaviors that lead to cancer, including smoking tobacco, drinking alcohol, overweight/obesity, and lack of exercise. The report, issued by the International Agency for Research on Cancer (IACR), contains contributions from more than […]

IBD Linked to Increased Risk of Certain Cancers

IMNG Medical Media, 2014 Jan 07, D Brunk February 03, 2014 Full Story Immunosuppressive therapies for inflammatory bowel disease do not appear to be implicated in the increased risk for melanomas and hematologic malignancies seen in these patients, based on the results of a large database analysis and a separate meta-analysis published in the February […]