Atherosclerosis

Excess blood sugar promotes clogging of arteries: Study

Cornell University Health News | March 23, 2021 Excess sugar in the blood, the central feature of diabetes, can react with immune proteins to cause myriad changes in the immune system, including inflammatory changes that promote atherosclerosis, according to a new study from scientists at Weill Cornell Medicine and University of Massachusetts Medical School. The […]

Serum Urate and Atherosclerosis: Ties Shown in Men

— Odds ratios doubled for coronary artery calcification among men, but not women, with high serum urate levels by Nancy Walsh, Senior Staff Writer, MedPage Today February 25, 2020 High levels of serum urate were associated with the presence of coronary artery calcification in men, though not in women, Swedish researchers found. In a multivariate […]

REDUCE-IT: 25% Reduction in MACE With High-Dose EPA

Sue Hughes September 25, 2018 High doses (4-g daily) of the omega-3 oil eicosapentaenoic acid (EPA) have shown a large benefit on cardiovascular events in the randomized, double-blind REDUCE-IT trial. Top-line results of the trial were announced yesterday in a press release by the sponsor, Amarin, which manufactures the high-dose EPA product under the brand name Vascepa. The study […]

Sesame oil extracts shown to reduce heart disease risk

University of Central Florida Health News | September 27, 2018 A product in your pantry may hold the secret to protecting the heart from disease. UCF researchers have found that sesame oil can prevent or reduce the development of the buildup of plaque in the artery walls, known as atherosclerosis. In a study recently published […]

Adherence to Mediterranean diet, high-sensitive C-reactive protein, and severity of coronary artery disease: Contemporary data from the INTERCATH cohort

Atherosclerosis August 2018 Volume 275, Pages 256–261 Christoph Waldeyer Highlights •The guidelines strongly recommend a healthy diet as a cornerstone of cardiovascular disease prevention. •An association with Mediterranean diet (MD) has been shown for different vascular beds. •There are no multivariate data regarding Mediterranean diet and the extent of coronary artery disease (CAD). •The present […]

Saturated fat does not clog the arteries: coronary heart disease is a chronic inflammatory condition, the risk of which can be effectively reduced from healthy lifestyle interventions

Aseem Malhotra British Journal of Sports Medicine Volume 51, Issue 15 Coronary artery disease pathogenesis and treatment urgently requires a paradigm shift. Despite popular belief among doctors and the public, the conceptual model of dietary saturated fat clogging a pipe is just plain wrong. A landmark systematic review and meta-analysis of observational studies showed no […]

Chlamydia and Heart Disease

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. How secure should you feel if your doctor tells you that your cholesterol levels are normal Are you immune to heart disease just because you have been informed you have normal cholesterol levels? If you have been a reader of my weekly articles for any length of time, you […]

HbA1c Tied to Progression of Aortic Stiffness Without Diabetes

February 08, 2017 TUESDAY, Feb. 7, 2017 (HealthDay News) — For individuals without diabetes, glycated hemoglobin (HbA1c) is associated with accelerated progression of aortic stiffness, according to a study published online Jan. 25 in Diabetes Care. Carmel M. McEniery, Ph.D., from the University of Cambridge in the United Kingdom, and colleagues examined the impact of […]

A Nutrient That Dissolves Arterial Plaque

The nutritional product policosanol not only dramatically slows down the progression of arterial narrowing, but actually reverses plaque. And it is safer, cheaper, and has additional biochemical benefits that the statins do not. Policosanol makes blood less likely to abnormally form clots by lowering fibrinogen (decreases platelet aggregation), something that statins do not do. In […]

Higher CV Risk Seen With Calcium Supplements

But observational study suggests benefit from dietary sources by Larry Husten October 13, 2016 Calcium supplements might increase cardiovascular risk, whereas dietary calcium was associated with a protective effect, a new observational study found. Many people — in particular, older women — take calcium supplements to prevent or treat osteoporosis, though the supporting evidence for […]

Persistent Nonalcoholic Fatty Liver Disease Increases Risk for Carotid Atherosclerosis

July 06, 2016 Gastroenterology TAKE-HOME MESSAGE The authors of this retrospective, cohort study evaluated the association between nonalcoholic fatty liver disease (NAFLD) and subsequent development of subclinical carotid atherosclerosis in 8020 men. They found that, compared with men without NAFLD, men with persistent NAFLD had significantly greater risk of incident subclinical carotid atherosclerosis (HR, 1.23; […]

New study shows aged garlic extract can reduce dangerous plaque buildup in arteries

Supplement can help prevent progression of heart disease Date: Januay 21, 2016 Source: Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) Summary: The supplement aged garlic extract can lower the risk of heart disease by reducing the accumulation of certain types of plaque in the arteries, a new study finds. The supplement […]

Fruit and Vegetable Consumption Associated With Lower Prevalence of Coronary Atherosclerosis

November 10, 2015 Circulation AKE-HOME MESSAGE Researchers evaluated participants of the CARDIA study to determine the association between intake of fruit and vegetables during young adulthood with coronary atherosclerosis later in life, finding that higher intake was associated with lower prevalence of coronary atherosclerosis (P < .001). The findings support high intake of fruit and […]

Fish Oil Supplementation and Markers of Atherothrombotic Risk in Cardiovascular Disease

March 03, 2015 The American Journal of Cardiology TAKE-HOME MESSAGE The association between fish oil supplementation and atherothrombotic risk was examined in patients with suspected coronary artery disease (CAD). Patients who received fish oil but not lipid-lowering therapy exhibited significantly lower levels of remnant lipoproteins, triglycerides, IDL-C, LDL-C, VLDL-C, collagen-induced platelet aggregation, AtherOx, shear elasticity, […]

Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms

Expert Rev Clin Pharmacol. 2015 Mar;8(2):189-99. doi: 10.1586/17512433.2015.1011125. Epub 2015 Feb 6. Statins stimulate atherosclerosis and heart failure: pharmacological mechanisms. Okuyama H1, Langsjoen PH, Hamazaki T, Ogushi Y, Hama R, Kobayashi T, Uchino H. Author information Abstract In contrast to the current belief that cholesterol reduction with statins decreases atherosclerosis, we present a perspective that statins may be causative in coronary artery […]

Cholesterol-Overloaded HDL Particles Are Independently Associated With Progression of Carotid Atherosclerosis

February 16, 2015 Journal of the American College of Cardiology TAKE-HOME MESSAGE The authors progressively followed patients who had baseline cholesterol molecules per HDL particle with serial carotid artery ultrasound measurements. In 5 years, the patients with the highest cholesterol per HDL ratios had almost 50% more carotid plaque develop. The findings suggest that the […]

Anti-inflammatory mechanism of dieting and fasting revealed

Date: February 16, 2015 Source: Yale University Summary: Researchers have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer’s disease. In their study, published in the Feb. 16 online issue ofNature […]

Cause-Effect: Vascular Disease and LBP

Atherosclerosis contributes to low back pain and spinal degeneration. By Deborah Pate, DC, DACBR Dynamic Chiropractic – January 1, 2015, Vol. 33, Issue 01 Atherosclerosis is a far-too-common chronic, systemic disease. We tend to think only of the clinical symptoms associated with this disease affecting the coronary arteries, as in a myocardial infarction; or the carotids, […]

HDL Cholesterol Efflux Capacity and Incident Cardiovascular Events

Anand Rohatgi, M.D. NEJM. November 20, 2014 Vol. 371 No. 21 November 18, 2014 10.1056/NEJMoa1409065 Abstract BACKGROUND It is unclear whether high-density lipoprotein (HDL) cholesterol concentration plays a causal role in atherosclerosis. A more important factor may be HDL cholesterol efflux capacity, the ability of HDL to accept cholesterol from macrophages, which is a key […]

Red Meat Bad for Heart Failure?

Video at MedPageToday as well. Published: Oct 28, 2014 | Updated: Oct 29, 2014 By Crystal Phend, Senior Staff Writer, MedPage Today Action Points Note that this cohort study demonstrated an association between baseline trimethylamine-N-oxide levels and subsequent mortality among patients with heart failure. Be aware that dietary histories were not obtained from the patients […]