Mechanisms

Immediate effects of spinal manipulation on nitric oxide, substance P and pain perception.

Man Ther. 2014 Oct;19(5):411-7. doi: 10.1016/j.math.2014.02.007. Epub 2014 Mar 5. Molina-Ortega F1, Lomas-Vega R1, Hita-Contreras F2, Plaza Manzano G3, Achalandabaso A1, Ramos-Morcillo AJ1, Martínez-Amat A1. Abstract Previous studies have analyzed the effects of spinal manipulation on pain sensitivity by using several sensory modalities, but to our knowledge, no studies have focused on serum biomarkers involved […]

Immediate Changes After Manual Therapy in Resting-State Functional Connectivity as Measured by fMRI in Participants With Induced Low Back Pain

J Manipulative Physiol Ther. 2014 Oct 2. pii: S0161-4754(14)00171-7. doi: 10.1016/j.jmpt.2014.09.001. [Epub ahead of print] Immediate Changes After Manual Therapy in Resting-State Functional Connectivity as Measured by Functional Magnetic Resonance Imaging in Participants With Induced Low Back Pain. Gay CW1, Robinson ME, George SZ3, Perlstein WM4, Bishop MD5. Abstract OBJECTIVE: The purposes of this study […]

Assessment of skin blood flow following spinal manual therapy

Man Ther. 2014 Sep 10. pii: S1356-689X(14)00177-5. doi: 10.1016/j.math.2014.08.011. [Epub ahead of print] Assessment of skin blood flow following spinal manual therapy: A systematic review. Zegarra-Parodi Abstract Skin blood flow (SBF) indexes have been used to describe physiological mechanisms associated with spinal manual therapy (SMT). The aims of the current review were to assess methods […]

Short-Term Effect of Spinal Manipulation on Pain Perception, Spinal Mobility, and Full Height Recovery in Male Subjects With Degenerative Disk Disease – Full Text

Archives of Physical Medicine and Rehabilitation Volume 95, Issue 9, Pages 1613–1619, September 2014 Felipe Vieira-Pellenz, PT, PhD Abstract Objective To evaluate the short-term effect on spinal mobility, pain perception, neural mechanosensitivity, and full height recovery after high-velocity, low-amplitude (HVLA) spinal manipulation (SM) in the lumbosacral joint (L5-S1). Design Randomized, double-blind, controlled clinical trial with […]

Short-term effect of spinal manipulation on pain perception, spinal mobility, and full height recovery in male subjects with degenerative disk disease

Short Term Effects of Spinal Manipulation The Study: Short-term effect of spinal manipulation on pain perception, spinal mobility, and full height recovery in male subjects with degenerative disk disease: a randomized controlled trial. The Facts: The treatment was high velocity low amplitude manipulation of the L5-S1 area. The subjects were men with degenerative joint disease. […]

Immediate effects of spinal manipulation on nitric oxide, substance P and pain perception

Manual Therapy Volume 19, Issue 5, Pages 411–417, October 2014 Abstract Previous studies have analyzed the effects of spinal manipulation on pain sensitivity by using several sensory modalities, but to our knowledge, no studies have focused on serum biomarkers involved in the nociceptive pathway after spinal manipulation. Our objectives were to determine the immediate effect […]

The effects of spinal mobilizations on the sympathetic nervous system: A systematic review

Manual Therapy Volume 19, Issue 4, August 2014, Pages 281-287 Systematic review Laura Kingston Abstract The activity of the sympathetic nervous system is of importance to manual therapists, since the experience of pain is associated with sympathetic activity. There has been little exploration into the effects of mobilizing vertebral segments below the cervical spine. In […]

Does inter-vertebral range of motion increase after spinal manipulation? A prospective cohort study *- Full Text Article

Chiropr Man Therap. 2014 Jul 1;22:24. doi: 10.1186/s12998-014-0024-9. eCollection 2014. Branney J1, Breen AC2. Author information Abstract BACKGROUND: Spinal manipulation for nonspecific neck pain is thought to work in part by improving inter-vertebral range of motion (IV-RoM), but it is difficult to measure this or determine whether it is related to clinical outcomes. OBJECTIVES: This […]

Does inter-vertebral range of motion increase after spinal manipulation? A prospective cohort study

Published: 01 July 2014 Jonathan Branney & Alan C Breen Chiropractic & Manual Therapies volume 22, Article number: 24 (2014) Abstract Background Spinal manipulation for nonspecific neck pain is thought to work in part by improving inter-vertebral range of motion (IV-RoM), but it is difficult to measure this or determine whether it is related to […]

The effects of spinal mobilizations on the sympathetic nervous system

Laura Kingston Manual Therapy Volume 19, Issue 4 , Pages 281-287, August 2014 Abstract The activity of the sympathetic nervous system is of importance to manual therapists, since the experience of pain is associated with sympathetic activity. There has been little exploration into the effects of mobilizing vertebral segments below the cervical spine. In addition […]

Long-Term Lumbar Multifidus Muscle Atrophy Changes Documented With Magnetic Resonance Imaging With Spinal Manipulation

Long-Term Lumbar Multifidus Muscle Atrophy Changes Documented With Magnetic Resonance Imaging: A Case Series Mark Woodham J Radiol Case Rep. May 2014; 8(5): 27–34. Published online May 31, 2014. doi: 10.3941/jrcr.v8i5.1401 Abstract A retrospective case series of three patients with chronic low back pain who received baseline MRI scans revealing multifidus muscle atrophy with fatty […]

Immediate Changes After Manual Therapy in Resting-State Functional Connectivity as Measured by fMRI in Participants With Induced Low Back Pain

Charles W. Gay, DC Journal of Manipulative & Physiological Therapeutics Received: April 18, 2014; Received in revised form: August 18, 2014; Accepted: September 1, 2014; Published Online: October 02, 2014 DOI: http://dx.doi.org/10.1016/j.jmpt.2014.09.001 Abstract Objective The purposes of this study were to use functional magnetic resonance imaging to investigate the immediate changes in functional connectivity (FC) […]

Does specificity of manipulation matter in the treatment of chronic low back pain?

Posted on 10 April, 2014 by Joe Brence Recently, many in the manual therapy community have been questioning the mechanisms of how spinal manipulation works.  While some hold onto the belief that spinal manipulation has more of a biomechanical and structural influence, others believe the effects to be neurophysiological.    In a 2011 study published in […]

Changes in Biochemical Markers of Pain Perception and Stress Response After Spinal Manipulation

Authors: Gustavo Plaza-Manzano, PT Journal of Orthopaedic & Sports Physical Therapy, 2014 Volume: 44 Issue:4 Pages:231–239 DOI: 10.2519/jospt.2014.4996 Study Design Controlled, repeated-measures, single-blind randomized study. Objectives To determine the effect of cervical or thoracic manipulation on neurotensin, oxytocin, orexin A, and cortisol levels. Background Previous studies have researched the effect of spinal manipulation on pain […]

Low back pain relief associated with disc hydration after spinal manipulative therapy

J Orthop Sports Phys Ther. 2014 Jan;44(1):19-29. doi: 10.2519/jospt.2014.4967. Epub 2013 Nov 21. The within-session change in low back pain intensity following spinal manipulative therapy is related to differences in diffusion of water in the intervertebral discs of the upper lumbar spine and L5-S1. Beattie PF1, Butts R, Donley JW, Liuzzo DM. Abstract STUDY DESIGN: […]

Manual medicine and orthopedics

von Heymann W, et al. Orthopade. 2013 Oct;42(10):834-41. doi: 10.1007/s00132-013-2094-0. Article in German. Affiliation Praxis für Manuelle Medizin/Chirotherapie, Orthopädische Praxisgemeinschaft, Schwachhauserheerstr. 367, 28211, Bremen, Deutschland, vonheymann@aerzteseminar-mwe.de. Abstract Manual medicine (MM) is a manual medical technique to identify and treat reversible dysfunction especially of the musculoskeletal system. The origins of MM were derived from empirical observations […]

The Biology of Manual Therapies

Brian C. Clark, PhD JAOA Full Text Article:  http://www.jaoa.org/content/112/9/617.full JAOA Full Text PDF:  http://www.jaoa.org/content/112/9/617.full.pdf+html Abstract Each year, more than 18 million adults in the United States receive manual therapies, at a total annual out-of-pocket cost of $3.9 billion. Although there is growing evidence supporting the efficacy of manual therapies, little is known about the mechanisms […]

Non-thrust manual therapy reduces erector spinae short-latency stretch reflex asymmetries in patients with chronic low back pain

Goss DA Jr,et al. J Electromyogr Kinesiol. 2012 Oct;22(5):663-9. doi: 10.1016/j.jelekin.2012.01.004. Epub 2012 Jan 28. Affiliation Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH 45701, USA. Abstract The purpose of this study was to determine if non-thrust manual therapy (MT) attenuated side-to-side differences (asymmetry) of the erector spinae (ES) stretch reflex amplitude in nine […]

Immediate effects of region-specific and non-region-specific spinal manipulative therapy in patients with chronic low back pain

Immediate effects of region-specific and non-region-specific spinal manipulative therapy in patients with chronic low back pain: a randomized controlled trial. Randomized controlled trial de Oliveira RF, et al. Phys Ther. 2013. Show full citation Abstract BACKGROUND: Manual therapists typically advocate the need for a detailed clinical examination to decide which vertebral level should be manipulated in […]

Chiropractic Adjustments Produce Immediate Results Visible on MRI

Magnetic resonance imaging zygapophyseal joint space changes (gapping) in low back pain patients following spinal manipulation and side-posture positioning: a randomized controlled mechanisms trial with blinding. Cramer GD, Cambron J, Cantu JA, Dexheimer JM, Pocius JD, Gregerson D, Fergus M, McKinnis R, Grieve TJ. J Manipulative Physiol Ther. 2013 May;36(4):203-17. doi: 10.1016/j.jmpt.2013.04.003. Epub 2013 May […]