Primary Care News · January 08, 2024 Prenatal Acetaminophen Use Linked to Poorer Early Language Development Third-trimester use linked to poorer language outcomes among male children FRIDAY, Jan. 5, 2024 (HealthDay News) — Prenatal acetaminophen use during pregnancy is associated with poorer early language development, especially among male offspring, according to a study published online […]
Regular Acetaminophen Use and Blood Pressure in People With Hypertension: The PATH-BP Trial Iain M. MacIntyre, Emma J. Turtle, Tariq E. Farrah, Catriona Graham, James W. Dear and David J. Webb and for the PATH-BP (Paracetamol in Hypertension–Blood Pressure) Investigators* Originally published 7 Feb 2022https://doi.org/10.1161/CIRCULATIONAHA.121.056015Circulation. 2022;145:416–423 Abstract Background: Acetaminophen is widely used as first-line therapy […]
The Science of Pain-Killers A user’s guide to over-the-counter analgesics like acetaminophen, ibuprofen, and more Paul Ingraham • Jun 30, 2021 • 15m read Ordinary pain-killers like ibuprofen and acetaminophen are fairly safe and somewhat effective in moderation and work in different ways, so cautious experimentation is justified for many people. They are all roughly […]
Wayne Kuznar, for MDLinx | July 20, 2018 Nearly three fourths of patients who present with acetaminophen-induced acute liver injury (ALI) or failure (ALF) are women, according to findings from a North American registry. Women with acetaminophen overdose leading to ALI/ALF were more likely than men to present with high-grade hepatic encephalopathy and have critical […]
Marlene Busko February 19, 2018 Acetaminophen (paracetamol) use has been linked with a depletion of sulfated sex hormones in a large metabolomic study, and the findings suggest that fetal exposure to the drug could even be linked with risk of male urogenital malformation at birth. Acetaminophen has been used for over 50 years, and more […]
January 26, 2014 at 7:29 am ATLANTA, Ga. (CBS Atlanta) – A new study has found that fever treatments may cause thousands of more flu deaths each season. To find the effects of widespread use of medications that suppress fever, researchers created mathematical models. Researchers found that fever-reducing drugs like acetaminophen and ibuprofen may lead […]
By NICHOLAS BAKALAR DECEMBER 14, 2016 Long-term use of pain relievers may increase the risk for hearing loss, according to new findings. Researchers prospectively tracked the use of pain relievers and self-reported hearing loss in 55,850 women over six years. They found that compared with women who used nonsteroidal anti-inflammatory drugs (such as ibuprofen or naproxen) two […]
Neil Osterweil November 15, 2013 BOSTON, Massachusetts — The link between acetaminophen (Tylenol and generics) and liver damage is well established, but there is also evidence to suggest that in some asymptomatic patients, therapeutic doses of acetaminophen and light-to-moderate alcohol use can lead to renal disease. An examination of data from a nationwide health survey […]
Megan Brooks February 24, 2014 Prenatal exposure to acetaminophen ― a drug considered safe in pregnancy ― may raise the risk for behavioral problems in children, including attention-deficit/hyperactivity disorder (ADHD) and hyperkinetic disorder (HKD), a severe form of ADHD, new research suggests. “Because the exposure and outcomes are frequent, these results are of public health […]
The Family Health Guide Understanding the differences between acetaminophen and NSAIDs Once upon a time, easing pain was relatively simple: take two aspirin and call the doctor in the morning. Now there are many pain relievers to choose from (see “Pain relievers at a glance”). Willow bark was one of the earliest painkillers. Extracts or […]
Janis C. Kelly May 28, 2015 Acetaminophen (paracetamol) overdose caused one fifth of all cases of acute liver failure leading to the need for liver transplant (ALFT) in seven European countries, according to a study published online May 28 in the British Journal of Clinical Pharmacology. However, when researchers compared in-country rates of acetaminophen-linked AFLT […]
Troy Brown, RN March 02, 2015 Paracetamol, known as acetaminophen in the United States, may have more risks than originally thought, particularly when it is taken at the higher end of standard therapeutic doses, according to a new systematic review. The authors and an outside expert recommend caution when interpreting the data, as they are observational in […]
January 14, 2015 Annals of Internal Medicine TAKE-HOME MESSAGE In this meta-analysis, researchers assessed 137 studies to determine the efficacy of treatments for knee osteoarthritis. Hyaluronic acid was considered the most effective for pain control, and acetaminophen was considered the least effective. Intra-articular corticosteroids did not improve function when compared with placebo, and none of […]
Megan Brooks DisclosuresJanuary 09, 2015 In a drug safety communication issued today, the US Food and Drug Administration (FDA) says it is aware of recent reports “questioning” the safety of prescription and over-the-counter (OTC) pain medicines when used during pregnancy, but that it lacks adequate studies to change current recommendations. The benefits and risks of using prescription […]
Ricki Lewis, PhD January 07, 2015 Despite the prevalence of knee osteoarthritis (OA), few studies compare treatments head-to-head. Now, a network meta-analysis compares 137 reports on the effectiveness of such treatments and reveals that acetaminophen, the most widely used over-the-counter treatment, does not provide a clinically significant reduction in pain. “Except for celecoxib, all active interventions were […]
Published time: 25 Feb, 2014 21:14 Over-the-counter pain relievers made with acetaminophen are among the most widely-sold in the United States, but concerns raised by a new study could possibly change all of that. Researchers at the University of California Los Angeles say that acetaminophen — the effective ingredient in popular retail drugs including Excedrin […]