Use of often prescribed drugs against arthritis and pain increases the risk of dying from a stroke. This is the conclusion of a major new registry study involving more than 100,000 patients. 2014.11.13 | LOTTE FISKER JØRGENSEN It is older versions of COX-2 inhibitors, which are now linked to increased risk of dying from a […]
COX-2 Inhibitors Linked to Stroke Mortality Sue Hughes November 06, 2014 Further evidence suggesting harm of cyclooxygenase-2 (COX-2) inhibitors in patients with stroke has been reported, with this latest study showing these agents to be associated with an increased risk for stroke mortality. The study, published online in Neurology on November 5, was conducted by a team led by […]
Gwen M.C. Masclee Gastroenterology Volume 147, Issue 4, Pages 784–792.e9, October 2014 Background & Aims Concomitant use of nonsteroidal anti-inflammatory drugs (NSAIDs) and low-dose aspirin increases the risk of upper gastrointestinal bleeding (UGIB). Guidelines suggest avoiding certain drug combinations, yet little is known about the magnitude of their interactions. We estimated the risk of UGIB […]
By Carole Alison Chrvala, PhD Take Note Results from case-control studies suggest that nonselective NSAIDs and COX-2 inhibitors are associated with an increased risk of atrial fibrillation, with the highest risk evident for new and long-term users, particularly older persons and those with a history of chronic kidney disease. This association has important clinical implications […]
(Here’s more on Vitamin B6 on this site: https://www.integrative-archives.com/category/nutrition/vitamin-b6/) Chang HY,et al. Am J Clin Nutr. 2013 Dec;98(6):1440-9. doi: 10.3945/ajcn.113.064477. Epub 2013 Oct 23. Abstract BACKGROUND: A low circulating vitamin B-6 concentration, which is an independent risk factor for cardiovascular disease, is commonly seen in human inflammation. OBJECTIVE: We investigated whether cyclooxygenase inhibitors alter vitamin […]
Published: May 30, 2013 | Updated: May 30, 2013 By Michael Smith , North American Correspondent, MedPage Today Action Points In this large meta-analysis diclofenac, ibuprofen, and coxibs all significantly increased major coronary events. Naproxen did not significantly increase major vascular events, but heart failure risk was roughly doubled by all NSAIDs. High doses of […]