February 16, 2018 Pain TAKE-HOME MESSAGE Individuals aged >50 years with spinal stenosis were randomized to receive epidural injections of local anesthetic with corticosteroid (n = 200) or local anesthetic only (n = 200) to evaluate the risk of cortisol suppression associated with epidural corticosteroids. Cortisol reduction of >50% at 3 weeks was seen in […]
MARCH 29, 2016 Ensuring diagnosis matches the indication is key, experts emphasize Properly used, epidural spinal injections are an effective way to manage chronic spinal pain, according to the results of a systematic review of the available literature. Published in Pain Physician (2015;18:E939-E1004), the study’s investigators, including first author and that journal’s editor-in-chief Alan […]
Judith A. Racoosin, M.D., M.P.H, Sally M. Seymour, M.D., Laurelle Cascio, Pharm.D., and Rajdeep Gill, Pharm.D. N Engl J Med 2015; 373:2299-2301December 10, 2015DOI: 10.1056/NEJMp1511754 At times, the Food and Drug Administration (FDA) must grapple with safety concerns related to off-label uses of FDA-approved medications. Over the past several years, we have sought to understand […]
By NICHOLAS BAKALAR AUGUST 24, 2015 Steroid shots are commonly used for back pain, but evidence that they work no better than placebos is mounting. In a review published Monday in Annals of Internal Medicine, researchers combined data from 30 placebo-controlled studies of epidural steroid injections for radiculopathy (back pain that radiates to the legs) […]
The JAMA Network > Share on twitter Share on facebook Share on citeulike Share on google_plusone_share More Sharing Services May 5, 2015, Vol 313, No. 17 < Previous in this Issue | Next in this Issue > PDF Viewpoint Published online May 5, 2015 Improving the Safety of Epidural Steroid Injections FREE Honorio T. Benzon, MD1; Marc A. Huntoon, MD2; James P. Rathmell, MD3 [+] Author Affiliations JAMA. 2015;313(17):1713-1714. doi:10.1001/jama.2015.2912. 8,404Views 0Citations View Metrics This […]
Pauline Anderson November 28, 2014 Epidural steroid injections (ESIs) should be contraindicated under certain circumstances in the management of back pain, the US Food and Drug Administration’s (FDA’s) Anesthetic and Analgesic Drug Products Advisory Committee has concluded. After 2 days of presentations and discussions, committee members agreed that injecting a particulate steroid in the cervical […]
ISSUE: NOVEMBER 2014 | VOLUME: 12(11) The FDA’s warning that use of epidural steroid injections (ESIs) may result in “rare but serious adverse events, including loss of vision, stroke, paralysis and death” drew a strong response from societies whose members offer such pain treatments. The FDA required the addition of a warning to the labels […]
Anesthesiology. 2014 Nov;121(5):1045-55. doi: 10.1097/ALN.0000000000000409. Epidural Steroid Injections, Conservative Treatment, or Combination Treatment for Cervical Radicular Pain: A Multicenter, Randomized, Comparative-effectiveness Study. Cohen SP1, Hayek S, Semenov Y, Pasquina PF, White RL, Veizi E, Huang JH, Kurihara C, Zhao Z, Guthmiller KB, Griffith SR, Verdun AV, Giampetro DM, Vorobeychik Y. Abstract BACKGROUND: Cervical radicular pain […]