Glucocorticoids

Local Steroid Injection for Carpal Tunnel Syndrome

November 10, 2021 JAMA Network Open TAKE-HOME MESSAGE This follow-up to a double-blind, placebo-controlled RCT sought to explore whether local steroid injection (with 80 mg or 40 mg of methylprednisolone) versus saline impacted long-term carpal tunnel pain scores and rates of carpal tunnel release surgery, as well as other outcomes such as time to surgery. The […]

Limited guidance available on use of corticosteroid injections for knee arthritis

March 25, 2019 LAS VEGAS — Although corticosteroid injections appear to offer short-term benefits regarding pain and function for patients with knee arthritis, a presenter here noted no guidance is available in the terms of frequency and dosage. In his presentation at The Knee Society Specialty Day at the American Academy of Orthopedic Surgeons Annual […]

Knee osteoarthritis: Steroid injections offer no benefit, study suggests

Medical News Today Tuesday 16 May 2017 By Honor Whiteman Patients with symptomatic knee osteoarthritis do not benefit from steroid injections, concludes a new study published in JAMA. Study co-author Timothy E. McAlindon, of Tufts Medical Center in Boston, MA, and colleagues found that steroid injections administered every 3 months were no better than a placebo for alleviating […]

Pain Management Injection Therapies for Low Back Pain

Technology Assessment Report Roger Chou, MD, FACP, Robin Hashimoto, PhD, Janna Friedly, MD, Rochelle Fu, PhD, Tracy Dana, MLS, Sean Sullivan, PhD, Christina Bougatsos, MPH, and Jeffrey Jarvik, MD, MPH. Pacific Northwest Evidence-based Practice Center Rockville (MD): Agency for Healthcare Research and Quality (US); 2015 Mar 20. Structured Abstract Objectives: Low back pain is common and injections […]

Intra-articular Injection of Hyaluronate Versus Corticosteroid in Adhesive Capsulitis

Tae Kang Lim, MD; Kyoung Hwan Koh, MD; Min Soo Shon, MD; Seung Won Lee, MD; Young Eun Park, MD; Jae Chul Yoo, MD Orthopedics October 2014 – Volume 37 · Issue 10: e860-e865 DOI: 10.3928/01477447-20140924-51 Abstract The goal of this study was to prospectively compare the early clinical results of intra-articular injection of hyaluronate […]

Steroid injections added to the usual treatment of lumbar radicular syndrome

BMC Musculoskelet Disord. 2014 Oct 11;15(1):341. doi: 10.1186/1471-2474-15-341. Steroid injections added to the usual treatment of lumbar radicular syndrome: a pragmatic randomized controlled trial in general practice. Spijker-Huiges A, Winters JC, van Wijhe M, Groenier K. Abstract BACKGROUND: Lumbosacral radicular syndrome (LRS) is a self-limiting, benign, painful and impairing condition caused by lumbar disc herniation […]

Significant link found between osteonecrosis and corticosteroids

Dilisio MF. Orthopedics. 2014. doi:10.3928/01477447-20140626-54. Story Source A low but statistically significant link was determined between osteonecrosis and short-term, low-dose oral corticosteroids, according to study findings. Researchers utilized a software platform to evaluate data from 24,533,880 patients who received either single or multiple methylprednisolone taper pack (MTP) prescriptions during a 12-year span. They then compared […]

Daily Inhaled Corticosteroids Marginally Stunts Children’s Growth

Frontline Medical News, 2014 Jul 16 MA Moon Daily use of low- to medium-dose inhaled corticosteroids for mild to moderate persistent asthma suppresses growth to a “small” degree in children of all ages, according to a Cochrane review published online July 16 in the Cochrane Database of Systematic Reviews. This level of use was associated […]

FDA Orders New Warning for Epidural Steroids

Published: Apr 23, 2014 By John Gever, Deputy Managing Editor, MedPage Today Injectable corticosteroids must now carry a new label warning about the risks of severe adverse effects from epidural injections including death, stroke, and permanent blindness and paralysis, the FDA said. The agency decided that such a warning is needed after reviewing numerous reports […]

Spinal Corticosteroids Run Risk of Severe Neuro Effects

Robert Lowes April 23, 2014 Epidural injections of corticosteroids to relieve pain — a widespread, off-label use — run the rare risk for blindness, stroke, paralysis, and death, the US Food and Drug Administration (FDA) announced today. The FDA is requiring manufacturers of corticosteroids to revise drug labels to include this warning. In today’s announcement, […]

The effectiveness of physiotherapeutic interventions in treatment of frozen shoulder/adhesive capsulitis

The effectiveness of physiotherapeutic interventions in treatment of frozen shoulder/adhesive capsulitis: A systematic review Tarang K. Jain Journal of Back and Musculoskeletal Rehabilitation Volume 27, Number 3 / 2014 Wednesday, November 27, 2013 Abstract BACKGROUND AND OBJECTIVE: Frozen shoulder is a common condition, yet its treatment remains challenging. In this review, the current best evidence […]

Treatment of the sacroiliac joint in patients with leg pain-comparing manual therapy, PT and intra-articular injeciton

A randomized-controlled trial L. H. Visser European Spine Journal October 2013, Volume 22, Issue 10, pp 2310-2317 Abstract Purpose The sacroiliac joint (SIJ) may be a cause of sciatica. The aim of this study was to assess which treatment is successful for SIJ-related back and leg pain. Methods Using a single-blinded randomised trial, we assessed […]

Glucocorticoids Boost Risk of Blood Clots

Glucocorticoid use significantly increased the risk of venous thromboembolism (VTE) among current, new, and continuing users of the anti-inflammatory agents

Spine Injections May Set Stage for Fractures

Published: Jun 7, 2013 | Updated: Jun 10, 2013 By Elizabeth DeVita Raeburn , Contributing Writer, MedPage Today Download Complementary Copy of Article Action Points Lumbar epidural steroid injections are often prescribed for the treatment of radiculopathy or neurogenic claudication arising from compression of spinal nerves. In this retrospective cohort study, an increasing number of […]

Subacromial impingement syndrome: effectiveness of pharmaceutical interventions

Nonsteroidal anti-inflammatory drugs, corticosteroid, or other injections: a systematic review The term subacromial impingement syndrome (SIS) encompasses a wide range of disorders, including rotator cuff syndrome, tendinopathy of the various rotator cuff tendons and bursitis in the shoulder region. The prescription of analgesics (often NSAIDs) and corticosteroid injections is common in primary care. This systematic […]

Management of chronic tendon injuries

Childress MA,et al. Am Fam Physician. 2013 Apr 1;87(7):486-90. Abstract Chronic tendon injuries present unique management challenges. The assumption that these injuries result from ongoing inflammation has caused physicians to rely on treatments demonstrated to be ineffective in the long term. Nonsteroidal anti-inflammatory drugs should be limited in the treatment of these injuries. Corticosteroid injections […]

Drugs for relief of pain in patients with sciatica

Systematic review and meta-analysis Rafael Zambelli Pinto, PhD student BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e497 (Published 13 February 2012) Cite this as: BMJ 2012;344:e497 Abstract Objective To investigate the efficacy and tolerability of analgesic and adjuvant pain drugs typically administered in primary care for the management of patients with sciatica. Design Systematic review. Data source International […]

Drugs for relief of pain in patients with sciatica

Systematic review and meta-analysis BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e497 (Published 13 February 2012) Cite this as: BMJ 2012;344:e497 Sciatica is considered to be a prognostic indicator of poor outcome among patients with low back pain. Furthermore a substantial proportion continuing to have persistent pain for two years or longer. General practitioners often prescribe pain-relieving drugs […]

How Effective and Save Are Systemic Steroids for Acute Low Back Pain

Mark Johnson, D.O. Evidence-Based Answers From The Family Physicians Inquires Network Clinical Inquires Short courses of systemic steroids are likely safe, but they are ineffective. A single dose of intramuscular (IM) or intravenous (FV) methylprednisolone doesn’t improve long-term pain scores in patients with low back pain and sciatica and produces conflicting effects on furiction. Oral prednisone (9-day taper) doesn’t improve pain or […]