Yoo TK, Han KD, Kim DH, et al Cancer Epidemiology, Biomarkers & Prevention|June 1, 2020 A nationwide cohort with risk stratification according to risk factors for breast cancer was examined for the association between hormone replacement therapy (HRT) and breast cancer. Data from 4,558,376 postmenopausal women who underwent breast cancer screening and regular health checkups […]
March 19, 2018 Stroke; A Journal of Cerebral Circulation TAKE-HOME MESSAGE The authors of this literature review summarize woman-specific stroke risk factors, such as hormones, estrogens, and pregnancy. In addition, age at menarche and menopause impacts the stroke risk in women. Unique in this paper is a discussion of exogenous estrogen and testosterone for transgender […]
04.04.2016 by Molly Walker Contributing Writer For women who used hormone replacement therapy to treat menopausal symptoms, risk of blood clots tended to vary depending on the type of therapy used, a small Swedish case-control study found. While the risk of venous thromboembolism (VTE) was moderately higher with estrogen-only therapy compared with untreated, age-matched controls, […]
Kate Johnson October 05, 2015 LAS VEGAS — In the first year after a postmenopausal women discontinues hormone therapy, her risk for cardiovascular mortality is higher than if she had continued the therapy, according to an observational study. Hormone therapy guidelines for postmenopausal women recommend the lowest dose for the briefest period. “This has led […]
Quality of Life and Hypertension After Hormone Therapy Withdrawal in New York City Michelle P. Warren, MD, Olivia Richardson, BA, Sonal Chaudhry, MD, Aimee D. Shu, MD, Yael Swica, MD, Valerie R. Sims, BA, and Nancy L. Sloan, DrPH Disclosures Menopause. 2013;20(12):1255-1263. Abstract Objective: Many women stopped hormone therapy (HT) or estrogen therapy (ET) after […]
February 25, 2015 The Lancet TAKE-HOME MESSAGE The authors examined 52 epidemiological studies to evaluate the relationship between hormone therapy and ovarian cancer risk. Of the total of 12,110 postmenopausal women who were diagnosed with ovarian cancer, 55% had used hormone therapy. Risk was increased in current users, even with Hormone therapy may have a […]
Menopausal hormone use and ovarian cancer risk: individual participant meta-analysis of 52 epidemiological studies The Lancet, 02/17/2015 Half the epidemiological studies with information about menopausal hormone therapy and ovarian cancer risk remain unpublished, and some retrospective studies could have been biased by selective participation or recall. Authors aimed to assess with minimal bias the effects […]
By Carole Alison Chrvala, PhD Reviewed by Philip Green, MD, Assistant in Clinical Medicine, Division of Cardiology, Department of Medicine, Columbia University Medical Center, NY Full Story Take Note A modest, statistically significant increase in the risk of atrial fibrillation (AF) was evident for women who had previously undergone hysterectomy and were treated with estrogen […]
Published: Feb 13, 2014 | Updated: Feb 13, 2014 By Kristina Fiore, Staff Writer, MedPage Today Full Story Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. Moderate physical activity confers a […]
Published: Jan 28, 2014 By Kristina Fiore, Staff Writer, MedPage Today Full Story Full Text Article Download from MedPageToday Action Points Use of postmenopausal hormone replacement therapy was associated with increased risk of acute pancreatitis, researchers found. The risk did not differ by current or past use, but it seemed to be higher among women […]
JAMA 2013 Oct 01;310(13)1353-1368, JE Manson, RT Chlebowski, ML Stefanick, AK Aragaki, JE Rossouw, RL Prentice, G Anderson, BV Howard, CA Thomson, AZ Lacroix, J Wactawski-Wende, RD Jackson, M Limacher, KL Margolis, S Wassertheil-Smoller, SA Beresford, JA Cauley, CB Eaton, M Gass, J Hsia, KC Johnson, C Kooperberg, LH Kuller, CE Lewis, S Liu, LW […]
Be aware that while estrogen plus progestin therapy may increase the risk of breast cancer, this evidence suggests that estrogen therapy alone may carry some protection against breast cancer for women without a uterus.
Published: Sep 30, 2013 | Updated: Oct 1, 2013 By Michael Smith Full MedPageToday Article: http://www.medpagetoday.com/OBGYN/HRT/41965 Action Points For postmenopausal women, conjugated equine estrogens (CEEs) use was associated with a higher risk of incident venous thrombosis and possibly myocardial infarction than estradiol use. Note that CEEs were not associated with an increased risk of ischemic stroke […]
Published: Mar 29, 2013 By Nancy Walsh , Staff Writer, MedPage Today Full Story: http://www.medpagetoday.com/OBGYN/HRT/38162 Action Points Note that this observational cohort study demonstrated an increased risk of invasive breast cancers among women taking estrogen-plus-progestin hormone replacement therapy (HRT) after menopause. Be aware that the overall incidence of breast cancer in users of HRT was […]
J. Natl. Cancer Inst. 2013 Sep 03;[EPub Ahead of Print], N Hou, S Hong, W Wang, OI Olopade, JJ Dignam, D TAKE-HOME MESSAGE In this retrospective analysis examining the impact of hormone replacement therapy (HRT) on the incidence of breast cancer, authors determined that race, body mass index, and breast density each influenced the risk […]