Marijuana

Cannabis Use Disorder Tied to Incident Cardiovascular Disease Events

October 14, 2023 Higher risk for incident events seen over seven years of follow-up THURSDAY, Oct. 12, 2023 (HealthDay News) — Adults with cannabis use disorder (CUD) have a higher risk for incident adverse cardiovascular disease (CVD) events when compared with matched adults without CUD, according to a study published online Sept. 27 in Addiction. […]

Recreational Cannabis Use a Negative for Adolescent Mental Health

— Even “subdiagnostic” use associated with adverse psychological events, study says by Elizabeth Short, Staff Writer, MedPage Today May 4, 2023 Cannabis use that doesn’t rise to the level of diagnosable substance abuse disorder was nonetheless associated with negative affects on mental health, national data showed. In the 2015 to 2019 National Surveys on Drug […]

What is long-term cannabis use doing to our brains?

By Joe Hannan | Medically reviewed by Amanda Zeglis, DO, MBA | Published August 17, 2022 Key Takeaways A 2022 study found that long-term cannabis users had cognitive deficits and lower hippocampal volume at age 45 compared with non-users and users of other substances. Legalization and decriminalization efforts, coupled with medical marijuana programs, may be […]

Research shows pain relieving effects of CBD

Date:  April 25, 2021 Source:  Syracuse University Summary:  In an experimental pain study of CBD in humans, researchers conclude that CBD pain relief is driven by both pharmacological action and psychological placebo effects. It’s been hailed as a wonder drug and it’s certainly creating wonder profits. By some estimates, the Cannabidiol (or CBD) market could […]

Immune Responses Regulated by Cannabidiol

Cannabis and Cannabinoid Research James M. Nichols and Barbara L.F. Kaplan Published Online:4 Sep 2019 https://doi.org/10.1089/can.2018.0073 Abstract Introduction: Cannabidiol (CBD) as Epidiolex® (GW Pharmaceuticals) was recently approved by the U.S. Food and Drug Administration (FDA) to treat rare forms of epilepsy in patients 2 years of age and older. Together with the increased societal acceptance […]

An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies – Full Text Article

Cannabis and Cannabinoid Research Vol. 2, No. 1 Kerstin Iffland and Franjo Grotenhermen Published Online:1 Jun 2017 https://doi.org/10.1089/can.2016.0034 Abstract Introduction: This literature survey aims to extend the comprehensive survey performed by Bergamaschi et al. in 2011 on cannabidiol (CBD) safety and side effects. Apart from updating the literature, this article focuses on clinical studies and CBD […]

Driving Under the Influence of Cannabis An Increasing Public Health Concern – Full Text Article

March 26, 2018 Johannes G. Ramaekers, PhD Driving is a complex task that requires integrity of sensory, motor, and cognitive function. The driving task may be compromised by factors related to the vehicle, the driving environment, and the driver. Driver impairment is a major cause of motor vehicle crashes and commonly results from alcohol intoxication.1 […]

Attenuation of early phase inflammation by cannabidiol prevents pain and nerve damage in rat osteoarthritis – Full Text Article

Pain. 2017 Dec; 158(12): 2442–2451. Published online 2017 Sep 1. doi: [10.1097/j.pain.0000000000001052] Holly T. Philpott Abstract Osteoarthritis (OA) is a multifactorial joint disease, which includes joint degeneration, intermittent inflammation, and peripheral neuropathy. Cannabidiol (CBD) is a noneuphoria producing constituent of cannabis that has the potential to relieve pain. The aim of this study was to […]

Cannabis as a Substitute for Opioid-Based Pain Medication: Patient Self-Report – Full Text Article

Cannabis and Cannabinoid Research Vol. 2, No. 1 Amanda Reiman, Mark Welty, and Perry Solomon Published Online:1 Jun 2017 https://doi.org/10.1089/can.2017.0012 Abstract Introduction: Prescription drug overdoses are the leading cause of accidental death in the United States. Alternatives to opioids for the treatment of pain are necessary to address this issue. Cannabis can be an effective treatment […]

Lifetime Marijuana Use and Cognitive Function in Middle Age

February 10, 2016 JAMA internal medicine TAKE-HOME MESSAGE Data from the Coronary Artery Risk Development in Young Adults study were used to evaluate the relationship between cumulative lifetime marijuana use and cognitive function in middle age. Current use of marijuana increased the risk of deficits in verbal memory and processing speed. After adjusting for confounding […]

Cannabis for the Management of Pain

December 09, 2015 The Journal of Pain: Official journal of the American Pain Society TAKE-HOME MESSAGE A cohort of 215 current or previous users of medical cannabis with non-cancer pain were dispensed an herbal cannabis product and were then matched with 216 controls with chronic pain but not using cannabis. After 1-year follow-up with a […]

White matter damage caused by ‘skunk-like’ cannabis, study shows

Date: November 27, 2015 Source: King’s College London Summary: Smoking high potency ‘skunk-like’ cannabis can damage a crucial part of the brain responsible for communication between the two brain hemispheres, according to a new study. Smoking high potency ‘skunk-like’ cannabis can damage a crucial part of the brain responsible for communication between the two brain […]

Multicenter study examines safety of medical cannabis in treatment of chronic pain

Date: September 29, 2015 Source: McGill University Health Centre Summary: A Canadian research team has completed a national multicenter study looking at the safety of medical cannabis use among patients suffering from chronic pain. They found that patients with chronic pain who used cannabis daily for one year, when carefully monitored, did not have an […]

Pot Smoking May Increase Prediabetes Risk

09.13.2015 by Salynn Boyles Contributing Writer Marijuana use in early adulthood was associated with an increased risk for prediabetes, but not diabetes, by middle adulthood in an adjusted analysis of data from the Coronary Artery Risk Development in Young Adults (CARDIA) study. Current marijuana use was associated with a 65% increase in prediabetes risk and […]

Cannabinoids for Pain—Time to Consider?

August 31, 2015 Written by Robert Bonakdar MD, FAAFP Recently, The Journal of the American Medical Association (JAMA) has been a leading venue for research on medical marijuana. In October 2014, an analysis appearing in JAMA Internal Medicine noted that states which enacted medical cannabis laws had a 24.8% lower mean annual opioid overdose mortality […]

Cannabinoid Offers Modest Relief From Pain, Spasticity

06.23.2015 by Sarah Wickline Wallan Staff Writer, MedPage Today Various cannabinoid compounds did not improve nausea, vomiting, or appetite, and only slightly improved chronic pain and spasticity, in patients with various long-term health conditions, a review of randomized clinical trials found. The greatest reductions in chronic pain were reported by patients who smoked tetrahydrocannabinol (THC) […]

Marijuana shows potential in treating autoimmune disease

Date: June 2, 2014 Source: University of South Carolina Summary: Researchers have discovered a novel pathway through which marijuana’s main active constituent, THC, can suppress the body’s immune functions. The recent findings show that THC can change critical molecules of epigenome called histones, leading to suppression of inflammation. A team of University of South Carolina […]

Pot a Common Remedy to Ease Back Pain

Published: Oct 11, 2013 By John Fauber Full Story:  http://www.medpagetoday.com/MeetingCoverage/AdditionalMeetings/42228 NEW ORLEANS — Use of marijuana to ease back pain was common among patients at a university spine clinic in Colorado where pot has been legal for medical purposes since 2000, but most of the users did not have a prescription, according to research presented […]