Arch Phys Med Rehabil. 2023 Mar 23;S0003-9993(23)00160-0. doi: 10.1016/j.apmr.2023.02.022. Fabio Zaina PMID: 36963709 DOI: 10.1016/j.apmr.2023.02.022 Abstract Objective: To Identify evidence-based rehabilitation interventions for persons with non-specific low back pain (LBP) with and without radiculopathy and to develop recommendations from high-quality clinical practice guidelines (CPGs) to inform the World Health Organization’s (WHO) Package of Interventions for […]
November 07, 2021 BMJ : British Medical Journal TAKE-HOME MESSAGE This comprehensive systematic review and network meta-analysis assesses the efficacy and safety of multiple preparations and doses of NSAIDs, opioids, and acetaminophen for clinically relevant reductions in pain caused by knee and hip osteoarthritis. The review includes nearly 200 randomized controlled trials comprised of over 100,000 […]
Kanae Togo PhD,Nozomi Ebata PhD,Naohiro Yonemoto PhD,Lucy Abraham MSc CPsychol, First published: 19 September 2021 https://doi.org/10.1111/papr.13079 Abstract Purpose This study aimed to assess the safety risks associated with using nonsteroidal anti-inflammatory drugs (NSAIDs) in elderly patients (≥65 years) compared with younger patients (<65 years) with osteoarthritis (OA) and/or chronic low back pain (CLBP). Methods A retrospective analysis […]
The Science of Pain-Killers A user’s guide to over-the-counter analgesics like acetaminophen, ibuprofen, and more Paul Ingraham • Jun 30, 2021 • 15m read Ordinary pain-killers like ibuprofen and acetaminophen are fairly safe and somewhat effective in moderation and work in different ways, so cautious experimentation is justified for many people. They are all roughly […]
William A. Tucker, MD; Mitchell C. Birt, MD; Archie A. Heddings, MD; Greg A. Horton, MD Orthopedics. https://doi.org/10.3928/01477447-20200428-06 Posted May 7, 2020 Abstract The association of nonsteroidal anti-inflammatory drugs (NSAIDs) with non-union in long bone fractures has been controversial. The purpose of this study was to evaluate whether NSAID exposure results in increased risk of […]
Injections $988 Physical Therapy: $510 Bracing: $193 Chiropractic services: $193 Narcotics: $101 Gabapentin: $93 NSAIDs: $47 Spine (Phila Pa 1976). 2019 Jul 1;44(13):937-942. doi: 10.1097/BRS.0000000000002983. Barton C Abstract STUDY DESIGN: Retrospective, observational study. OBJECTIVE: To examine the costs associated with nonoperative management (diagnosis and treatment) of cervical radiculopathy in the year prior to anterior […]
Wheatley, Benjamin M., MD; Nappo, Kyle E., MD; Christensen, Daniel L., MD; Holman, Ann M., MLS; Brooks, Daniel I., PhD; Potter, Benjamin K., MD JAAOS – Journal of the American Academy of Orthopaedic Surgeons: April 1, 2019 – Volume 27 – Issue 7 – p e330–e336 doi: 10.5435/JAAOS-D-17-00727 Introduction: NSAIDs inhibit osteogenesis and may result […]
Don’t expect relief to last beyond a few months by Nancy Walsh, Senior Staff Writer, MedPage Today March 29, 2019 Pain relief from nonsteroidal anti-inflammatory drugs (NSAIDs) in knee osteoarthritis (OA) was rapid but declined over time, a large meta-analysis demonstrated. Data from 72 randomized controlled trials found that statistically significant reductions in pain peaked […]
Reuters Health News | September 24, 2018 The commonly used painkiller diclofenac may be linked with an increased risk of heart problems, a large Danish study suggests. Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that’s often used to treat arthritis and other painful joint conditions. In many countries, it’s available without a prescription. Researchers found […]
More evidence of NSAID risk in early pregnancy Reuters Health News | June 21, 2018 Using non-steroidal anti-inflammatory drugs (NSAIDs) around the time of conception significantly increases the risk of miscarriage in the first 8 weeks of pregnancy, a study suggests. Researchers compared newly pregnant women who used NSAIDs around the time of conception or […]
Musculoskeletal Science and Practice Volume 33, February 2018, Pages 67-70 Vahid Abdollah Highlights The signal intensity weighted centroid (SIWC) is a novel reliable non-invasive method for quantifying the effects of loading. Except for a more anterior SIWC in the L4L5 disc after extension, there were no significant SIWC differences. No significant differences were found in […]
February 21, 2018 The Journal of Family Practice TAKE-HOME MESSAGE The authors evaluated the published evidence to compare the effectiveness of oral non-steroidal anti-inflammatory drugs (NSAIDs) with that of other oral analgesics such as opioids and acetaminophen for pain in acute musculoskeletal injury. The authors observe that NSAIDs are at least as effective as other […]
January 26, 2014 at 7:29 am ATLANTA, Ga. (CBS Atlanta) – A new study has found that fever treatments may cause thousands of more flu deaths each season. To find the effects of widespread use of medications that suppress fever, researchers created mathematical models. Researchers found that fever-reducing drugs like acetaminophen and ibuprofen may lead […]
Date: January 26, 2018 Source: Boston University School of Medicine Summary: Chances are you or someone you know has used nonsteroidal anti-inflammatory drugs (NSAIDs) within the last month. NSAIDs, such as Advil (ibuprofen), Aleve (naproxen) and Celebrex, are among the most commonly used medicines in the US. Now, for the first time, researchers have found […]
From: WebMd By Tim Locke TUESDAY Jan. 9, 2018 — Taking the common painkiller ibuprofen has been linked in a small study with a condition affecting male fertility problems. Male fertility is dropping around the world and the researchers wanted to see if ibuprofen might be contributing to this. Ibuprofen Ibuprofen is a non-steroidal anti-inflammatory drug sold without a […]
May 24, 2017 BMJ : British Medical Journal TAKE-HOME MESSAGE In this meta-analysis of individual patient data, investigators examined records from Canadian and European healthcare databases to determine if exposure to an oral non-steroidal anti-inflammatory drug (NSAID) was associated with an increased risk of acute myocardial infarction (MI). Data from 446,763 individuals were included; 61,460 […]