Don’t expect relief to last beyond a few months by Nancy Walsh, Senior Staff Writer, MedPage Today March 29, 2019 Pain relief from nonsteroidal anti-inflammatory drugs (NSAIDs) in knee osteoarthritis (OA) was rapid but declined over time, a large meta-analysis demonstrated. Data from 72 randomized controlled trials found that statistically significant reductions in pain peaked […]
More evidence of NSAID risk in early pregnancy Reuters Health News | June 21, 2018 Using non-steroidal anti-inflammatory drugs (NSAIDs) around the time of conception significantly increases the risk of miscarriage in the first 8 weeks of pregnancy, a study suggests. Researchers compared newly pregnant women who used NSAIDs around the time of conception or […]
Date: January 26, 2018 Source: Boston University School of Medicine Summary: Chances are you or someone you know has used nonsteroidal anti-inflammatory drugs (NSAIDs) within the last month. NSAIDs, such as Advil (ibuprofen), Aleve (naproxen) and Celebrex, are among the most commonly used medicines in the US. Now, for the first time, researchers have found […]
Eur Heart J Cardiovasc Pharmacother. 2017 Apr 1;3(2):100-107. doi: 10.1093/ehjcvp/pvw041. Sondergaard KB Abstract AIMS: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and have been associated with increased cardiovascular risk. Nonetheless, it remains unknown whether use of NSAIDs is associated with out-of-hospital cardiac arrest (OHCA). METHODS AND RESULTS: From the nationwide Danish Cardiac Arrest Registry, all […]
By NICHOLAS BAKALAR DECEMBER 14, 2016 Long-term use of pain relievers may increase the risk for hearing loss, according to new findings. Researchers prospectively tracked the use of pain relievers and self-reported hearing loss in 55,850 women over six years. They found that compared with women who used nonsteroidal anti-inflammatory drugs (such as ibuprofen or naproxen) two […]
The Family Health Guide Understanding the differences between acetaminophen and NSAIDs Once upon a time, easing pain was relatively simple: take two aspirin and call the doctor in the morning. Now there are many pain relievers to choose from (see “Pain relievers at a glance”). Willow bark was one of the earliest painkillers. Extracts or […]
Clinical Pain Medicine ISSUE: OCTOBER 2015 | VOLUME: 13(10) Short-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) negatively affected fertility in normally cycling women, in a new study. Researchers observed a dramatic decrease in progesterone, a hormone essential for ovulation, after only 10 days of treatment. “This study confirms that the administration of diclofenac, naproxen and […]
Marlene Busko April 15, 2014 SEATTLE, WA — Patients receiving an anticoagulant for deep vein thrombosis (DVT) or pulmonary embolism (PE) who take a nonsteroidal anti-inflammatory drug (NSAID) or aspirin for pain or headache, even for a few days, are at heightened risk for a major bleed, according to a new study published online April […]
Published: Feb 11, 2014 By John Gever, Deputy Managing Editor, MedPage Toda Full Story In 16-9 vote, the FDA advisory committee assessing NSAID safety said the warning label on naproxen should not be changed to suggest it has a better cardiovascular risk profile than other drugs in this class. Those voting “No” on the question […]
Published: Feb 9, 2014 | Updated: Feb 9, 2014 By Todd Neale, Senior Staff Writer, MedPage Today Full Story Two FDA advisory committees will meet Monday and Tuesday to consider the significance of recent evidence surrounding the cardiovascular risks of nonsteroidal anti-inflammatory drugs (NSAIDs), including studies pointing to lower risks with naproxen. The FDA put […]
FDA: Naproxen May Pose Lower CV Risk IMNG Medical Media, 2014 Jan 29, A Ault February 03, 2014 Full Story The Food and Drug Administration says that the nonsteroidal anti-inflammatory drug naproxen may carry a lower risk of cardiovascular thromboembolic events than that of other selective or nonselective NSAIDs. The agency presented evidence for that […]
Alzheimers Dement 2013 Nov 01;9(6)724-732, KR Obermann, JC Morris, CM Roe Research · December 19, 2013 Full Story: http://www.practiceupdate.com/journalscan/7193 Journal Abstract: http://www.alzheimersanddementia.com/article/S1552-5260(12)02574-5/abstract TAKE-HOME MESSAGE Results of this exploratory analysis of 100 drugs showed that common medications used by older adults, 10% in this study, are associated with increases or decreases in cognitive performance. Further studies […]
Published: May 30, 2013 | Updated: May 30, 2013 By Michael Smith , North American Correspondent, MedPage Today Action Points In this large meta-analysis diclofenac, ibuprofen, and coxibs all significantly increased major coronary events. Naproxen did not significantly increase major vascular events, but heart failure risk was roughly doubled by all NSAIDs. High doses of […]
Aspirin, Nonsteroidal Anti-inflammatory Drug Use, and Risk for Crohn Disease and Ulcerative Colitis: A Cohort Study Ashwin N. Ananthakrishnan, MD, MPH 6 March 2012, Vol 156, No. 5 Ann Intern Med. 2012;156(5):350-359. doi:10.7326/0003-4819-156-5-201203060-00007 Background: Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory but have been linked in some studies to Crohn disease (CD) and ulcerative […]
Published: Nov 1, 2011 By Joyce Frieden , News Editor, MedPage Today Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. Explain that women who use nonsteroidal anti-inflammatory drugs for 15 or […]