Eur Heart J Cardiovasc Pharmacother. 2017 Apr 1;3(2):100-107. doi: 10.1093/ehjcvp/pvw041. Sondergaard KB Abstract AIMS: Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and have been associated with increased cardiovascular risk. Nonetheless, it remains unknown whether use of NSAIDs is associated with out-of-hospital cardiac arrest (OHCA). METHODS AND RESULTS: From the nationwide Danish Cardiac Arrest Registry, all […]
By NICHOLAS BAKALAR DECEMBER 14, 2016 Long-term use of pain relievers may increase the risk for hearing loss, according to new findings. Researchers prospectively tracked the use of pain relievers and self-reported hearing loss in 55,850 women over six years. They found that compared with women who used nonsteroidal anti-inflammatory drugs (such as ibuprofen or naproxen) two […]
The Family Health Guide Understanding the differences between acetaminophen and NSAIDs Once upon a time, easing pain was relatively simple: take two aspirin and call the doctor in the morning. Now there are many pain relievers to choose from (see “Pain relievers at a glance”). Willow bark was one of the earliest painkillers. Extracts or […]
May 30, 2016 Increased risk of small bowel injury for healthy participants treated with celecoxib + PPI HealthDay FRIDAY, May 27, 2016 (HealthDay News) — Proton pump inhibitors (PPIs) increase the risk of nonsteroidal anti-inflammatory drug-induced small bowel injury, according to a study published in the June issue of Clinical Gastroenterology and Hepatology. Ema Washio, […]
The Lancet, 03/25/2016 da Costa BR, et al. Researchers sought to investigate the effectiveness of different preparations and doses of non–steroidal anti–inflammatory drugs (NSAIDs) on osteoarthritis pain in a network meta–analysis. It was determined that diclofenac 150 mg/day is the most effective NSAID for the treatment of pain and function in patients with osteoarthritis. Methods […]
March 08, 2016 JAMA : The Journal of the American Medical Association TAKE-HOME MESSAGE The authors of this clinical evidence synopsis reviewed the efficacy of topical nonsteroidal anti-inflammatory drugs (NSAIDs) for acute musculoskeletal pain caused by sprains, strains, and overuse. Good pain relief was reported, particularly with gel formations and some patches without an increase […]
By DailyHealthPost January 12, 2016 The healing powers of turmeric are impressive. Many studies have already demonstrated how the spice can help fight fatty liver disease, weight loss and even cancer. In many cases, turmeric can help heal diseases better than pharmaceutical drugs, such as prozac. A report in the journal Health Services Research found that […]
Clinical Pain Medicine ISSUE: OCTOBER 2015 | VOLUME: 13(10) Short-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) negatively affected fertility in normally cycling women, in a new study. Researchers observed a dramatic decrease in progesterone, a hormone essential for ovulation, after only 10 days of treatment. “This study confirms that the administration of diclofenac, naproxen and […]
Clinical Pain Medicine ISSUE: AUGUST 2015 | VOLUME: 13(8) There are no significant differences between giving nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids to patients in the emergency department (ED) with regard to their risk for developing chronic pain after motor vehicle accidents, a new study suggests. Individuals presenting to EDs after vehicular accidents have a […]
Clinical Pain Medicine ISSUE: JULY 2015 | VOLUME: 13(7) Taking a nonsteroidal anti-inflammatory drug (NSAID) with antithrombotic therapy after a myocardial infarction (MI) almost doubles the risk for bleeding compared with not using NSAIDs—even after short-term treatment, according to a study published in the Journal of the American Medical Association (2015;313:805-814). The cardiovascular event risk […]
Nancy A. Melville July 14, 2015 The combination of antidepressants and nonsteroidal anti-inflammatory drugs (NSAIDS) is linked to an early increased risk for intracranial hemorrhage, regardless of the type of NSAID or antidepressant, new research shows. “The take-home message for clinicians is that special attention should be paid [to] antidepressant users when they start an […]
If you regularly take a nonsteroidal antinflammatory drug (NSAID) for arthritis pain, you may be wondering if it’s safe. Here’s our advice. We’ve known for some time that NSAIDs are linked to potentially serious gastrointestinal (GI) and heart troubles. A study published in The Lancet helps characterize and quantify the cardiovascular and GI risks of […]