NSAIDs

Ligament Injury and Healing: A Review of Current Clinical Diagnostics and Therapeutics

R.A. Hauser The Open Rehabilitation Journal, 2013, 6, 1-20 Abstract: Ligament injuries are among the most common causes of musculoskeletal joint pain and disability encountered in primary practice today. Ligament injures create disruptions in the balance between joint mobility and joint stability, causing abnormal force transmission through the joint, which results in damage to other […]

Ibuprofen Kills Thousands Each Year, So What Is The Alternative?

Monday, June 4th 2012 A recent Reuters’ article opened with the following stunning sentence: “Long-term high-dose use of painkillers such as ibuprofen or diclofenac is ‘equally hazardous’ in terms of heart attack risk as use of the drug Vioxx, which was withdrawn due to its potential dangers, researchers said.”   The 2004 Vioxx recall, as […]

Aspirin, Nonsteroidal Anti-inflammatory Drug Use, and Risk for Crohn Disease and Ulcerative Colitis

Aspirin, Nonsteroidal Anti-inflammatory Drug Use, and Risk for Crohn Disease and Ulcerative Colitis: A Cohort Study Ashwin N. Ananthakrishnan, MD, MPH 6 March 2012, Vol 156, No. 5 Ann Intern Med. 2012;156(5):350-359. doi:10.7326/0003-4819-156-5-201203060-00007 Background: Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are anti-inflammatory but have been linked in some studies to Crohn disease (CD) and ulcerative […]

Drugs for relief of pain in patients with sciatica

Systematic review and meta-analysis Rafael Zambelli Pinto, PhD student BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e497 (Published 13 February 2012) Cite this as: BMJ 2012;344:e497 Abstract Objective To investigate the efficacy and tolerability of analgesic and adjuvant pain drugs typically administered in primary care for the management of patients with sciatica. Design Systematic review. Data source International […]

Drugs for relief of pain in patients with sciatica

Systematic review and meta-analysis BMJ 2012; 344 doi: http://dx.doi.org/10.1136/bmj.e497 (Published 13 February 2012) Cite this as: BMJ 2012;344:e497 Sciatica is considered to be a prognostic indicator of poor outcome among patients with low back pain. Furthermore a substantial proportion continuing to have persistent pain for two years or longer. General practitioners often prescribe pain-relieving drugs […]

NSAIDs May Up Women’s Risk of Crohn’s Disease

Published: Nov 1, 2011 By Joyce Frieden , News Editor, MedPage Today Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. Explain that women who use nonsteroidal anti-inflammatory drugs for 15 or […]

A systematic review on the effectiveness of pharmacological interventions for chronic non-specific low-back pain

T. Kuijpers European Spine Journal January 2011, Volume 20, Issue 1, pp 40-50 First online: 31 July 2010 Abstract The objective of this review was to determine the effectiveness of pharmacological interventions [i.e., non-steroid anti-inflammatory drugs (NSAIDs), muscle relaxants, antidepressants, and opioids] for non-specific chronic low-back pain (LBP). Existing Cochrane reviews for the four interventions […]

NSAIDs and Manipulation Ineffective for Acute Low Back Pain

Best Evidence Review Assessment of Diclofenac or Spinal Manipulative Therapy, or Both, in Addition to Recommended First-line Treatment for Acute Low Back Pain: A Randomized Controlled Trial Hancock MJ, Maher GC, Latimer J, et al Lancet. 2007;370:1638-1643 Full Story PubMed Reference Journal Reference Abstract Previous recommendations have noted that nonsteroidal anti-inflammatory drugs (NSAIDs) and spinal […]

A risk assessment of cervical manipulation vs. NSAIDs for the treatment of neck pain

Dabbs V, Lauretti WJ. J Manipulative Physiol Ther. 1995 Oct;18(8):530-6. Abstract OBJECTIVE: We reviewed the literature to evaluate the risk of serious injury or death resulting from cervical manipulation and to assess the evidence that cervical manipulation is an effective treatment for mechanical neck pain. We also reviewed the literature to assess the risks and […]

A risk assessment of cervical manipulation vs. NSAIDs for the treatment of neck pain

J Manipulative Physiol Ther. 1995 Oct;18(8):530-6. Dabbs V, Lauretti WJ. Abstract OBJECTIVE: We reviewed the literature to evaluate the risk of serious injury or death resulting from cervical manipulation and to assess the evidence that cervical manipulation is an effective treatment for mechanical neck pain. We also reviewed the literature to assess the risks and […]