Opioids

CDC Comes Down Hard on Opioids for Chronic Pain

03.15.2016 Urges physicians not to use opioids first-line for chronic pain by Kristina Fiore Associate Editor, MedPage Today The CDC has released its final guidance on opioid prescribing, urging clinicians not to use the painkillers as first-line therapy for chronic pain and suggesting limits on dose and duration when they do have to be prescribed. […]

One Month of Oral Morphine Decreases Gray Matter Volume in the Right Amygdala of Individuals with Low Back Pain: Confirmation of Previously Reported Magnetic Resonance Imaging Results

Pain Med. 2015 Dec 26. pii: pnv047. [Epub ahead of print] Lin JC1, Chu LF2, Stringer EA2, Baker KS3, Sayyid ZN2, Sun J2, Campbell KA4, Younger JW4. Abstract OBJECTIVE: . Prolonged exposure to opioids is known to produce neuroplastic changes in animals; however, few studies have investigated the effects of short-term prescription opioid use in […]

Long-term opioid use associated with increased risk of depression

Date: January 12, 2016 Source: Saint Louis University Summary: Opioids may cause short-term improvement in mood, but long-term use imposes risk of new-onset depression, a new study shows. The link was independent of the known contribution of pain to depression, and the study calls on clinicians to consider the contribution of opioid use when depressed […]

Study: Opioids, Muscle Relaxants Ineffective for Acute Low Back Pain

DECEMBER 04, 2015 Prescribing opioids and muscle relaxants to acute low back pain (LBP) patients who are already on nonsteroidal anti-inflammatory drugs (NSAIDs) does not provide additional pain relief, a new study suggests. There are more than 2.5 million acute LBP-related visits to emergency departments in the United States annually, where patients are often treated […]

Chronic Opioid Therapy After Lumbar Fusion Surgery for Degenerative Disc Disease in a Workers’ Compensation Setting

Spine: November 2015 – Volume 40 – Issue 22 – p 1775–1784 Anderson, Joshua T. BS Abstract Study Design. Retrospective cohort study. Objective. To evaluate prescription opioid use after lumbar fusion for degenerative disc disease in a workers’ compensation (WC) setting. Summary of Background Data. Use of opioids for treating chronic low back pain has […]

Naproxen With Cyclobenzaprine or Oxycodone/Acetaminophen for Acute Low-Back Pain

October 28, 2015 JAMA : The Journal of the American Medical Association TAKE-HOME MESSAGE Patients with acute non-traumatic, non-radicular low-back pain for In patients presenting to the emergency department with acute low-back pain, the addition of cyclobenzaprine or oxycodone/acetaminophen to naproxen had no clinical benefit over naproxen alone. Primary Care Written by David Rakel MD, […]

Opioid Prescriptions Common With Fibromyalgia

Patients taking opioids are less likely to subsequently receive guideline-recommended therapy TUESDAY, Oct. 20, 2015 (HealthDay News) — Opioid use is widespread among patients with newly diagnosed fibromyalgia, and patients taking opioids have a decreased likelihood of receiving guideline-recommended medications, according to a study published online Oct. 7 in Pain Practice. Rachel Halpern, Ph.D., M.P.H., […]

Naproxen With Cyclobenzaprine, Oxycodone/Acetaminophen, or Placebo for Treating Acute Low Back Pain

A Randomized Clinical Trial October 20, 2015 Benjamin W. Friedman, MD, MS Importance Low back pain (LBP) is responsible for more than 2.5 million visits to US emergency departments (EDs) annually. These patients are usually treated with nonsteroidal anti-inflammatory drugs, acetaminophen, opioids, or skeletal muscle relaxants, often in combination. Objective To compare functional outcomes and […]

PT and Chiro Care vs Opioids in Claims Duration

BMJ Open 2015;5:e007836 doi:10.1136/bmjopen-2015-007836 Rehabilitation medicine Association of worker characteristics and early reimbursement for physical therapy, chiropractic and opioid prescriptions with workers’ compensation claim duration, for cases of acute low back pain: an observational cohort study Jason W Busse Abstract Objective To assess the association between early reimbursement for physiotherapy, chiropractic and opioid prescriptions for […]

NSAIDs, Opioids Found Similar for Chronic Pain Risk After Vehicular Accidents

Clinical Pain Medicine ISSUE: AUGUST 2015 | VOLUME: 13(8) There are no significant differences between giving nonsteroidal anti-inflammatory drugs (NSAIDs) and opioids to patients in the emergency department (ED) with regard to their risk for developing chronic pain after motor vehicle accidents, a new study suggests. Individuals presenting to EDs after vehicular accidents have a […]

Orthopedic Surgeons Largely Contribute To Opioid Epidemic, Study Reveals

Understanding why physicians from various areas of expertise prescribe opioids helps the medical community as a whole combat opioid abuse, misuse and overdose. Even though emergency physicians are not likely to prescribe opioids to discharged patients, doctors from other medical fields are contributing to the opioid epidemic at a higher rate. Published in The Journal […]

A Randomized, Double-blind, Placebo-Controlled Crossover Trial of Oxymorphone Hydrochloride and Propoxyphene/Acetaminophen Combination for the Treatment of Neurogenic Claudication Associated With Lumbar Spinal Stenosis

Markman, John D. MD Spine15 May 2015Vol. 40 – Issue 10: p 684–691Abstract Study Design. Randomized, double-blind, placebo-controlled, single-dose crossover study. Objective. To test the analgesic efficacy of oxymorphone hydrochloride (OH) and propoxyphene/acetaminophen (PA) for patients with neurogenic claudication associated with lumbar spinal stenosis. Summary of Background Data. Although opioids are often prescribed for neurogenic […]

More than 1,000 deaths in Mass. last year linked to opioid overdoses

By Lynn Arditi Journal Staff Writer Posted Apr. 28, 2015 @ 2:12 pm Updated Apr 28, 2015 at 4:33 PM PROVIDENCE, R.I. – Massachusetts health officials said Tuesday that more than 1,000 deaths in 2014 are likely related to opioid overdoses, but the overdose death rate is still lower than Rhode Island’s. Based on those […]

Opioid-Induced Hyperalgesia in Chronic Pain

April 13, 2015 TAKE-HOME MESSAGE In order to determine the association of opioid use with heat pain perception, investigators evaluated 187 adults with chronic pain and found that those receiving opioids were more likely to be hyperalgesic than those who were not. Findings suggest that hyperalgesia is independently associated with long-term opioid use.   Abstract […]

Long-Acting Opioids Related to Unintentional Overdose Risk

Beth Skwarecki February 18, 2015 Long-acting opioids were associated with a greater than 2-fold risk for unintentional overdose compared with short-acting formulations, according to a cohort study published online February 16 in JAMA Internal Medicine. Moreover, the risk was more than 5-fold greater in the first 2 weeks of using a long-acting opioid. “If replicated in other cohorts, our findings […]

Trends in Opioid Analgesic Abuse and Mortality in the United States

Richard C. Dart, M.D. January 15, 2015 N Engl J Med 2015; 372:241-248 Abstract / Article Extract Background The use of prescription opioid medications has increased greatly in the United States during the past two decades; in 2010, there were 16,651 opioid-related deaths. In response, hundreds of federal, state, and local interventions have been implemented. […]

CDC Urges Caution on Opioid Prescribing in Young Women

Megan Brooks January 22, 2015 Opioid pain medications are widely prescribed among women of childbearing age, which is a “significant public health concern,” federal health officials with the Centers for Disease Control and Prevention said today. A new report published in the January 23 issue ofMorbidity and Mortality Weekly Report (MMWR) shows that roughly one fourth of privately insured women […]

Prescription painkillers’ overuse has become ‘silent epidemic’, US warns

Friday 16 January 2015 Alan Yuhas in New York In 2012, Americans received nearly 260 million prescriptions for opiate painkillers. Now, the National Institutes of Health (NIH) has released a white paper that reports “a dire need for research” to make up for the “scant” evidence that opioid painkillers should be used to treat chronic pain. The […]

FDA Urges Continued Caution for Pain Meds in Pregnancy

Megan Brooks DisclosuresJanuary 09, 2015 In a drug safety communication issued today, the US Food and Drug Administration (FDA) says it is aware of recent reports “questioning” the safety of prescription and over-the-counter (OTC) pain medicines when used during pregnancy, but that it lacks adequate studies to change current recommendations. The benefits and risks of using prescription […]

Opioids for low back pain

BMJ. 2015 Jan 5;350:g6380. doi: 10.1136/bmj.g6380. Opioids for low back pain. Deyo RA, Von Korff M, Duhrkoop D. Abstract Back pain affects most adults, causes disability for some, and is a common reason for seeking healthcare. In the United States, opioid prescription for low back pain has increased, and opioids are now the most commonly […]