Hyperglycemia

19 Jan
2021
Dementia, Endocrine System, Hemoglobin A1C, Hyperglycemia, Neurological System
By André Broussard, D.C.

HbA1c and brain health across the entire glycaemic spectrum

Diabetes, Obesity and Metabolism First published: 19 January 2021 Victoria Garfield PhD Abstract Aim To understand the relationship between HbA1c and brain health across the entire glycaemic spectrum. Materials and Methods We used data from the UK Biobank cohort consisting of 500,000 individuals aged 40–69 years. HbA1c and diabetes diagnosis were used to define baseline glycaemic […]

Read More
23 Mar
2018
Carbohydrates/High Glycemic, Cardiovascular System, Diabetes Type I, Diabetes Type II, Endocrine System, Gastrointestinal System, Hyperglycemia, Inflammation, Intestinal Hyperpermeability (Leaky Gut), Low Glycemic Diet, Metabolic Syndrome, Obesity
By André Broussard, D.C.

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Thaiss CA. Abstract Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse models of obesity and diabetes that hyperglycemia drives intestinal barrier permeability, through GLUT2-dependent transcriptional reprogramming of intestinal […]

Read More