Insulin Resistance

4 unintended consequences of antibiotic use

Naveed Saleh, MD, MS | January 8, 2021 In recent years, the gut microbiome has received much attention. The microbiota plays an important role in health and pathology. Hard-to-treat nosocomial infections in hospitalized patients, for instance, often derive from the microbiome, where antibiotic use selects for antibiotic-resistant organisms. Antibiotic use should always be carefully considered, […]

Vitamin D Could Lower the Risk of Developing Diabetes

Study demonstrates role of vitamin D in controlling glycemia Date: January 30, 2019 Source: The North American Menopause Society (NAMS) Summary: The benefits of vitamin D in promoting bone health are already well known. A new study suggests that vitamin D also may promote greater insulin sensitivity, thus lowering glucose levels and the risk of […]

Microbiome Intervention With Niacin Aids Insulin Sensitivity

– Delayed-release microcapsules of nicotinic acid induce favorable microbiome changes MONDAY, Dec. 18, 2017 (HealthDay News) — A targeted microbiome intervention, accomplished through microencapsulated delayed-release niacin, beneficially affects insulin sensitivity in humans, according to a study published online Dec. 6 in Diabetes Care. Daniela Fangmann, Ph.D., from the University of Kiel in Germany, and colleagues […]

Using Sucralose May Lead to Insulin Resistance in the Obese, Those Most Likely to Use the Sweetener

November 02, 2016 PracticeUpdate Editorial Team November 2, 2016—New Orleans, Louisiana— Sucralose may lead to insulin resistance in   people with obesity, according to new research from Washington University School of Medicine in St. Louis. The results were presented at ObesityWeek 2016, from October 31 – November 4. Marta Yanina Pepino de Gruev, PhD, now at […]

Antihistamines Block Gene Response to Exercise + Impair its Insulin-Sensitizing, Energizing & Hypotensive Effects

“An antihistamine is a type of pharmaceutical drug that opposes the activity of histamine receptors in the body,” that’s what Wikipedia knows about antihistamines. This, and the fact that there are H1-antihistamines and H2-antihistamines, that they target the histamine H1/2-receptors and that they are used to treat “problems” from allergic reactions in the nose (e.g., […]

High-Fructose Diet in Pregnancy Leads to Hypertension, Insulin Resistance, and Obesity in Adult Offspring

April 20, 2016 American Journal of Obstetrics and Gynecology TAKE-HOME MESSAGE Pregnant mice were randomized to receive 10% fructose solution or water as the sole drinking fluid throughout pregnancy to assess the effect of fructose-rich diets on cardiovascular disease risk factors in the offspring. Maternal and birth weights were similar in the two groups. At […]

Sleep Deprivation Is Associated With Reduced Insulin Sensitivity in Adolescents

April 01, 2016 JAMA Pediatrics TAKE-HOME MESSAGE The authors of this cross-sectional study evaluated the association between insulin sensitivity (by hyperglycemic clamp technique) and sleep deprivation in 615 adolescents. They found that sleep deprivation (<8 hours) was associated with reduced insulin (P = .02). Sleep deprivation was also associated with increases in age, BMI, waist […]

Interesting Article on “Insulin Dynamics”

Posted on September 28, 2015 This one has a bit for everyone. Relationship of Insulin Dynamics to Body Composition and Resting Energy Expenditure Following Weight Loss (Hron et al., 2015) I think study was actually done a few years ago, originally published here(blogged about here), and re-analyzed through the eyes of Chris Gardner.  I think. […]

Vitamin D Associated with Insulin Resistance In Women with PCOS

Mol Nutr Food Res. 2015 Aug 10. doi: 10.1002/mnfr.201500259. [Epub ahead of print] Vitamin D in polycystic ovary syndrome: Relationship to obesity and insulin resistance. Joham AE, Teede HJ, Cassar S, Stepto NK, Strauss BJ, Harrison CL, Boyle J, de Courten B. Abstract SCOPE: Polycystic ovary syndrome (PCOS) is underpinned by insulin resistance (IR). In […]

Dawn Phenomenon – Nutritional Suggestions

Posted on July 15, 2015 Many pre-diabetic, diabetic, and insulin resistant people have used the low carbohydrate diet to successfully manage their blood glucose levels.  It just plain works.  FACT (P<0.05). However, a small subset of this population fails to achieve normal fastingglucose.  This is likely due, in part, to a type of circadian mismatch induced […]

Patients With Psoriasis Are Insulin Resistant

March 23, 2015 Journal of the American Academy of Dermatology April 2015 Volume 72, Issue 4, Pages 599–605 TAKE-HOME MESSAGE Psoriasis is known to be associated with type 2 diabetes, but little is known about insulin sensitivity and psoriasis. The authors of this study used the hyperinsulinemic euglycemic clamp, which is the gold standard for […]

Why What You Eat Makes You Infertile

Dr. Mark’s Minute – Why What You Eat Makes You Infertile YouTube Link

Varying Walking Intensity Improves Type 2 Diabetes Control

Miriam E. Tucker August 04, 2014 Walking at alternating levels of intensity improves insulin sensitivity in people with type 2 diabetes, whereas walking at a continuous pace but expending the same amount of energy does not, a new study finds. The results were published online August 4, 2014 in Diabetologia by Kristian Karstoft, MD, of the Center of Inflammation and Metabolism, Rigshospitalet, […]

Relationship between insulin resistance and plasma vitamin D in adults

Badawi A Dovepress Journal Published Date July 2014 Volume 2014:7 Pages 297 – 303 DOI: http://dx.doi.org/10.2147/DMSO.S60569 Abstract: A recent relationship between vitamin D deficiency and the risk of type 2 diabetes mellitus (T2DM) and insulin resistance has been established through several studies. Research suggests a correlation between serum vitamin D and glycemic status measures. The […]

Can Exercise Enhance Insulin Sensitivity?

David Perlmutter, M.D. A lot depends on how our cells respond to the chemical insulin. Insulin is a hormone, created in the pancreas, that functions by enhancing the way cells take in glucose. Higher levels of dietary carbohydrates and sugars cause the pancreas to increase its output of insulin in response. Unfortunately, as insulin levels […]

Medical research related to low-carbohydrate diets

From Wikipedia, the free encyclopedia Low-carbohydrate diets became a major weight loss and health maintenance trend during the late 1990s and early 2000s.[1][2][3] While their popularity has waned recently from its peak, they remain popular.[4][5] This diet trend has stirred major controversies in the medical and nutritional sciences communities and, as yet, there is not a general consensus […]

Egg consumption and insulin metabolism in the Insulin Resistance Atherosclerosis Study (IRAS)

Lee CT Public Health Nutr. 2014 Jul;17(7):1595-602. doi: 10.1017/S1368980013001572. Epub 2013 Jun 19. PubMed Reference Journal Reference Abstract OBJECTIVE: To examine the association between egg consumption and measures of insulin sensitivity (SI), acute insulin response (AIR) and metabolic clearance rate of insulin (MCRI). DESIGN: Cross-sectional analysis. Settings Egg consumption, categorized as <1/week, 1 to <3/week, […]

Getting to the Underlying Cause of Obesity—PART 2: Weight Gain Without Obvious Abnormalities

Interview with Elizabeth Boham MD, MS, RD Interview by Tony Nimeh MD Dr. Tony Nimeh of PracticeUpdate talks with Dr. Elizabeth Boham of the UltraWellness Center in Lenox, Massachusetts, about managing obesity from the stance of functional medicine. In Part 1, Dr. Boham describes functional medicine and how it is uniquely positioned to help the […]

Yogurt and dairy product consumption to prevent cardiometabolic diseases: epidemiologic and experimental studies

American Journal of Clinical Nutrition, 04/03/2014  Clinical Article  Full Story PubMed Reference Journal Reference Astrup A – Dairy products contribute important nutrients to the diet, including energy, calcium, protein, and other micro– and macronutrients. However, dairy products can be high in saturated fats, and dietary guidelines generally recommend reducing the intake of saturated fatty acids (SFAs) to […]

Aerobic exercise and weight loss reduce vascular markers of inflammation and improve insulin sensitivity in obese women

Journal of the American Geriatrics Society, 03/21/2014 Clinical Article Ryan AS, et al. – The study aims to examine the relationships between plasma and tissue markers of systemic and vascular inflammation and obesity and insulin resistance and determine the effects of aerobic exercise training plus weight loss (AEX+WL) and weight loss (WL) alone on these […]