April 30, 2023 Researchers identify hundreds of thousands of cases of resulting diarrhea, candidiasis, and Clostridium difficile infections needing medical attention THURSDAY, April 27, 2023 (HealthDay News) — Overprescribing of antibiotics for acute upper respiratory infections (aURIs) causes significant patient harm, according to a study published in the April issue of the Journal of Internal […]
JAMA internal medicine TAKE-HOME MESSAGE Researchers retrospectively evaluated 754 patients with healthcare-associated Clostridium difficile infection to determine the association of proton pump inhibitor use (PPI) with recurrence. The hazard ratio for recurrence was 1.5 for continuous PPI use, and 47.1% of patients receiving PPIs had an evidence-based indication. Researchers suggest that PPI use without proper […]
The New England Journal of Medicine N Engl J Med 2015; 372:825-834February 26, 2015DOI: 10.1056/NEJMoa1408913 TAKE-HOME MESSAGE The authors of this study performed active surveillance across 10 geographic areas of the United States in 2011 to identify stool-positive cases of Clostridium difficile infection and classify them as community-associated or healthcare-associated. Of the total of 15,461 […]
February 03, 2015 Diagnosis and Treatment of Clostridium difficile in Adults JAMA : The Journal of the American Medical Association TAKE-HOME MESSAGE In this systematic review, 116 articles were analyzed to determine the best practices for Clostridium difficile (CDI) diagnosis and treatment in adults. Although C. difficile diagnostic testing is sometimes complex, several treatment options […]
Date: August 25, 2014 Source: University of Chicago Medical Center Summary: The presence of Clostridia, a common class of gut bacteria, protects against food allergies, a new study in mice finds. The discovery points toward probiotic therapies for this so-far untreatable condition. Food allergies affect 15 million Americans, including one in 13 children, who live […]
Published: Apr 30, 2014 By Elbert Chu The FDA failed to respond to a 2011 petition demanding strong warnings about proton pump inhibitors (PPIs), according to a Public Citizen’s lawsuit filed today. Public Citizen’s lawsuit seeks a ruling from the U.S. District Court of the District of Columbia that the FDA unlawfully withheld action, and calls for an […]
Herbert L. Dupont Clin Gastroenterol Hepatol. 2013;11(10):1216-1223. Abstract Clostridium difficileinfection (CDI) is increasing in frequency and severity in and out of the hospital, with a high probability of recurrence after treatment. The recent literature on CDI was reviewed using PubMed to include recent publications dealing with diagnosis and therapy. Real-time polymerase chain reaction is a […]