Fatty Liver

Effect of Phospholipid Curcumin Meriva® on Liver Histology and Kidney Disease Outcomes in Patients With NASH

July 10, 2024 Hepatology (Baltimore, Md.) TAKE-HOME MESSAGE This study assessed the safety and efficacy of treatment with phospholipid curcumin (Meriva®), a phospholipid formulation with ameliorated systemic curcumin absorption and delivery, in patients with NASH. A total of 52 patients with NASH (a majority of whom had fibrosis and chronic kidney disease) were randomized to […]

Drinking one soda or sweetened beverage per day may increase the risk of liver disease and cancers, according to new study

By Lisa Marie Basile | Fact-checked by Davi Sherman | Published September 20, 2023 Key Takeaways Findings from a new study published in JAMA explored the effects of sugary beverage intake in 98,786 postmenopausal women over an average follow-up of 20.9 years. They found that women who drank one or more servings daily of sweetened beverages—compared with […]

NAFLD tied to risk of gastrointestinal, lung, breast, and gynecological cancers

Reuters Health Medical News | March 26, 2021 People with non-alcoholic fatty liver disease (NAFLD) are at increased risk of developing several types of extrahepatic cancers, a meta-analysis of observational cohort studies suggests. Researchers examined data from 10 studies with a total of 182,202 participants (mean age 51 years), including 45,218 (24.8%) who had NAFLD […]

A Daily Dose of This Can Help Fight Chronic Conditions

by Naveed Saleh,MD May 19, 2020 When we think about sunlight and health, we usually associate exposure to the sun with negative consequences like sunburn and skin cancer. And it’s true—ultraviolet A and B radiation exposure can cause sunburn, damage to collagen fibers, vitamin A destruction in the skin, accelerated skin aging, as well as […]

Dietary vitamin E and C intake is inversely associated with the severity of nonalcoholic fatty liver disease

Digestive and Liver Diseases — Ivancovsky-Wajcman D, et al. | July 10, 2019 In this cross-sectional study involving a large cohort of subjects undergoing colonoscopy, researchers explored the association of dietary vitamins E and C intakes with nonalcoholic fatty liver disease (NAFLD), nonalcoholic steatohepatitis (NASH), and fibrosis markers. NAFLD’s presence was assessed by ultrasonography. Overall, […]

Heavier red meat consumption tied to higher NAFLD risk

Reuters Health News | February 13, 2019 People who eat a lot of animal protein may be more likely to have excessive fat in their livers and a higher risk of non-alcoholic fatty liver disease (NAFLD) than individuals whose main source of protein is vegetables, a Dutch study suggests. Researchers examined data from dietary questionnaires […]

Healthy diet alone reduces fatty liver

Naveed Saleh, MD, MS, for MDLinx | August 08, 2018 Maintaining a healthy diet is correlated with lower accumulation of fat in the liver and lower risk for developing hepatic steatosis, according to a recent analysis of the Framingham Heart Study published in Gastroenterology. Moreover, the benefits of healthy eating are compounded in patients genetically […]

Nonnutritive Sweeteners in Weight Management and Chronic Disease – Full Text Article

April 17, 2018 TAKE-HOME MESSAGE The authors reviewed recent studies evaluating the effects of nonnutritive sweeteners (NNSs) on body weight and on chronic diseases related to obesity. There is a positive association seen between NNS and body weight and related health conditions in cross-sectional and prospective cohort studies. Cellular and rodent models indicate a possible […]

How fruit juice affects the gut

FEBRUARY 07, 2018 Healthline/Medical News Today It was previously believed that fructose, which is the sugar found in fruit and fruit juice, is processed by the liver. However, a new study suggests that fructose is mainly processed in the small intestine. The study, which is published in the journal Cell Metabolism, reveals that processed high-sugar food and […]

Adherence to Mediterranean diet and non-alcoholic fatty liver disease: Effect on insulin resistance

The American Journal of Gastroenterology | October 27, 2017 Baratta F, et al. – For this research, the physicians examined the association between Mediterranean Diet (Med-Diet) and non-alcoholic fatty liver disease (NAFLD). In addition, they investigated the effect of Med-Diet on insulin resistance. An inverse relationship was found between Med-Diet and NAFLD prevalence. Good adherence […]

High Glycemic Index Diet Raises Hepatic Fat, Glycogen Stores

One-week high GI diet increases hepatic fat and glycogen stores compared with low GI diet   FRIDAY, Sept. 9, 2016 (HealthDay News) — A one-week high glycemic index (HGI) diet increases hepatic fat and glycogen stores in healthy adults compared with a low glycemic index (LGI) diet, according to a study published online Sept. 4 […]

Persistent Nonalcoholic Fatty Liver Disease Increases Risk for Carotid Atherosclerosis

July 06, 2016 Gastroenterology TAKE-HOME MESSAGE The authors of this retrospective, cohort study evaluated the association between nonalcoholic fatty liver disease (NAFLD) and subsequent development of subclinical carotid atherosclerosis in 8020 men. They found that, compared with men without NAFLD, men with persistent NAFLD had significantly greater risk of incident subclinical carotid atherosclerosis (HR, 1.23; […]

Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.

J Am Coll Nutr. 2016 May-Jun;35(4):346-53. doi: 10.1080/07315724.2015.1021057. Epub 2015 Jul 9. Farsi F1, Mohammadshahi M1, Alavinejad P2, Rezazadeh A3, Zarei M4, Engali KA5. Abstract BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder related to inflammation. Coenzyme Q10 (CoQ10) is a natural compound that has recently been considered as an anti-inflammatory factor. […]

Vitamin E May Benefit NASH Patients

11.18.2015 Pooled analysis: Improvements in liver histology, but no NASH resolution by Kristina Fiore Staff Writer, MedPage Today SAN FRANCISCO — Vitamin E was associated with improvement in liver histology in non-alcoholic steatohepatitis (NASH) patients whether or not they had diabetes, researchers reported here. In an analysis that pooled data from two trials, vitamin E […]

Vitamin E, Pentoxifylline Lower Liver Enzymes in NASH

10.20.2015 Two-thirds of treated patients had decreases in alanine aminotransferase by Nancy Walsh Senior Staff Writer, MedPage Today HONOLULU — Treatment of nonalcoholic steatohepatitis (NASH) with vitamin E and pentoxifylline led to improvements in liver enzymes, a real-world study found. In a study that included 106 patients given NASH-specific therapy, those in the treatment group […]

Associations of sugar and artificially sweetened soda with nonalcoholic fatty liver disease

Associations of sugar and artificially sweetened soda with nonalcoholic fatty liver disease: a systematic review and meta-analysis QJM: An International Journal of Medicine, 10/01/2015 Wijarnpreecha K, et al. Nonalcoholic fatty liver disease (NAFLD) is the major concern of public health worldwide. The risk of NAFLD in subjects who regularly drink soda is controversial. The aim […]

Drinking Sweet Beverages and Type 2 Diabetes: Beyond Obesity

Expert Opinion / Commentary · August 04, 2015 Written by Wahida Karmally DrPH, RD, CDE, CLS, FNLA Sugar is on the FDA “generally recognized as safe” list despite the growing body of evidence that sugar-sweetened beverage (SSB) consumption is detrimental to health and has been associated with increased risk of cardiovascular disease mortality,1 hypertension,2,3 liver […]

Fatty Liver Risk Increases With Daily Intake of Sugary Drinks

Diana Phillips June 11, 2015 Regular consumption of sugared beverages is associated with a greater prevalence of fatty liver disease, even after adjusting for body mass index, according to a large observational study. Specifically, adults who drank more than one sugar-sweetened drink per day were 55% (95% confidence interval [CI], 1.03 – 2.35) more likely […]

Daily sugar-sweetened beverage habit linked to non-alcoholic fatty liver disease

A daily sugar-sweetened beverage habit may increase the risk for non-alcoholic fatty liver disease (NAFLD), researchers from the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HRNCA) at Tufts University report in the Journal of Hepatology. The researchers analyzed 2,634 self-reported dietary questionnaires from mostly Caucasian middle-aged men and women enrolled in the National […]

Weight Loss Reduces Features of Fatty Liver

April 28, 2015 Weight Loss Reduces Features of Nonalcoholic Steatohepatitis Gastroenterology TAKE-HOME MESSAGE In this study, 293 patients with nonalcoholic steatohepatitis (NASH) were encouraged to make lifestyle changes over 1 year to reduce their weight. After 52 weeks, liver biopsies revealed that steatohepatitis had resolved in 25%, reductions in non-alcoholic fatty liver disease activity scores […]