Intestinal Hyperpermeability (Leaky Gut)

A Functional Medicine Approach to Fibromyalgia

Written by Amy Myers, MD It is estimated that fibromyalgia affects nearly 6 million or 1 in 50 people, causing chronic pain, particularly muscle pain, fatigue, sleep disturbances, brain fog, or cognitive impairment, depression, and painful tender points throughout the body. Not surprisingly, conventional medicine focuses only on managing symptoms through pain medications and antidepressants. […]

Defective epithelial barriers linked to 2 billion chronic diseases

MAY 6, 2021 by University of Zurich Humans are exposed to a variety of toxins and chemicals every day. According to the epithelial barrier hypothesis, exposure to many of these substances damages the epithelium, the thin layer of cells that covers the surface of our skin, lungs and intestine. Defective epithelial barriers have been linked […]

Treatment Interventions for the Management of Intestinal Permeability: A Cross-Sectional Survey of Complementary and Integrative Medicine Practitioners

The Journal of Alternative and Complementary Medicine Vol. 25, No. 6 Original Articles Bradley Leech, Janet Schloss, and Amie Steel Published Online:4 Jun 2019 https://doi.org/10.1089/acm.2018.0374 Abstract Objectives: This study aims to explore the treatment interventions complementary and integrative medicine (CIM) practitioners use in the management of an emerging health condition, increased intestinal permeability (IP), and […]

Probiotic for Leaky Gut Syndrome

The One Probiotic Supplement You Need to be Taking by David Perlmutter, MD Bowel wall permeability, more commonly described these days as “leaky gut,” is now front and center in the news, and is well known as a cause of a large number of common disease entities. The intestinal barrier that separates the luminal contents from […]

Leaky Gut, Leaky Brain: The Role of Zonulin

by Melissa Lee – Fx Medicine 05/13/2016 DOWNLOAD INFOGRAPHIC In recent years an amazing discovery has advanced our understanding of intestinal permeability. In 2000, Dr Alessio Fasano and his team discovered a molecule responsible for modulating intestinal tight junctions (TJs) known as zonulin. To date, zonulin is the only human protein known to reversibly regulate intestinal permeability. Based on Dr Fasano’s […]

6 Herbs and Nutrients to Repair Your Gut

If you’re experiencing symptoms such as seasonal allergies, brain fog, skin issues or hormonal imbalances, the root cause could be hiding in your digestive system. Every day, millions of people are struggling with leaky gut and other GI issues without even realizing it! Your gut is the gateway to health, as nearly 80% of your […]

Why L-Glutamine is the #1 Ingredient for Repairing Leaky Gut

Leaky gut is a modern epidemic that affects millions of people around the world—even though many of them aren’t aware of the underlying condition that causes symptoms ranging from digestive issues and mood imbalances to autoimmunity, cancer, and other chronic illnesses. Most conventional doctors fail to recognize the critical importance of gut health, or how a leaky […]

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Thaiss CA. Abstract Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse models of obesity and diabetes that hyperglycemia drives intestinal barrier permeability, through GLUT2-dependent transcriptional reprogramming of intestinal […]

Leaky Gut As a Danger Signal for Autoimmune Diseases – Full Text Article

Front. Immunol., 23 May 2017 | https://doi.org/10.3389/fimmu.2017.00598 Qinghui Mu The intestinal epithelial lining, together with factors secreted from it, forms a barrier that separates the host from the environment. In pathologic conditions, the permeability of the epithelial lining may be compromised allowing the passage of toxins, antigens, and bacteria in the lumen to enter the […]

Healing Leaky Gut Syndrome (Webinar Video)

Healing Leaky Gut Syndrome (Webinar Video) by Doni Wilson, ND

Bread and Other Edible Agents of Mental Disease

Front Hum Neurosci. 2016; 10: 130. Published online 2016 Mar 29. doi:  10.3389/fnhum.2016.00130 PMCID: PMC4809873 Paola Bressan* and Peter Kramer Author information ► Article notes ► Copyright and License information ► Go to: Abstract Perhaps because gastroenterology, immunology, toxicology, and the nutrition and agricultural sciences are outside of their competence and responsibility, psychologists and psychiatrists […]

Celiac Disease and Risk of Autoimmune Disorders

April 12, 2016 The Journal of Pediatrics TAKE-HOME MESSAGE Children with celiac disease (CD) were matched with healthy controls to evaluate the relative risk of type 1 diabetes mellitus (T1DM) and autoimmune thyroid disease. Children with CD were at significantly increased risk of developing hypothyroidism compared with controls (HR 4.64). There was also an increased […]

The neurons in our gut help the immune system keep inflammation in check

Date: January 22, 2016 Source: Rockefeller University Summary: The immune system must protect against potential infections, but over-vigilant reactions can cause problems. New research shows that neurons in the intestine send signals to immune cells to curb inflammation. The immune system exercises constant vigilance to protect the body from external threats–including what we eat and […]

Thyroid Health Part II: The Gluten, Gut, and Thyroid Connection

July 24th, 2015 Thyroid Health Part II: The Gluten, Gut, and Thyroid Connection This is the second article in a multi-part series on the thyroid. Follow along as we explore how the thyroid works and how you can use The Myers Way® Four Pillars of Health to prevent, control, or reverse thyroid disease. Last week […]

How our gut changes through our lifetimes, and how this determines our overall health

Date: May 21, 2015 Source: Norwich BioScience Institutes Summary: Scientists and clinicians have carried out the first detailed study of how our intestinal tract changes as we age, and how this determines our overall health.   This image shows the epithelial lining of the gut. Credit: Institute of Food Research and Univerisity of Siena Scientists […]

Leaky Gut – The Syndrome Linked to Many Autoimmune Diseases

by Jill Carnahan, MD on July 7, 2014   “Leaky Gut” Syndrome Hyperpermeability or “leaky gut” syndrome is the name given to a very common disorder in which the cells lining the intestines become “leaky” due to inflammation. The abnormally large spaces present between the cells of the gut wall allow the entry of toxic […]

Fatty liver may lead to a leaky gut

Liver injury in non-alcoholic steatohepatitis may lead to a leaky gut Posted on Fri, Apr 10, 2015 @ 09:22 AM According to new research published in Cellular and Molecular Gastroenterology and Hepatology, non-alcoholic steatohepatitis (NASH) is associated with intestinal hyperpermeability, which may worsen liver disease. NASH is the more severe form of non-alcoholic fatty liver disease […]

HOW TO HEAL A LEAKY GUT

CATHERINE GUTHRIE · MARCH 2015 Your intestines are home to a great deal of your digestive system, nervous system, and immune system. Here’s how to keep them healthy. Modern life is hard on your gut. Your entire digestive tract can be affected by stress, processed foods, alcohol, medications, and bacteria. All that chronic irritation can lead to inflammation and, […]

Confocal Endomicroscopy Shows Food-Associated Changes in the Intestinal Mucosa of Patients With Irritable Bowel Syndrome

Gastroenterology 2014 Nov;147(5):1012-20.e4. doi: 10.1053/j.gastro.2014.07.046. Epub 2014 Jul 30. Annette Fritscher-Ravens Abstract Background & aims: We investigated suspected food intolerances in patients with irritable bowel syndrome (IBS) using confocal laser endomicroscopy (CLE) for real-time visualization of structural/functional changes in the intestinal mucosa after food challenge. Patients with functional changes after food challenge (CLE+) were placed […]

Fermented Cabbage Juice

From:  The Nourishing Cook Ahhhh, cabbage juice tonic. A very simple yet refreshing Nourishing Traditions beverage! I think it will be the new Gatorade! No more will I need to rob my sauerkraut of its juice, as I can make separate ‘sauerkraut juice’. This is considered to be a super food tonic because of the […]