By Elizabeth W. Boham, M.D., M.S., R.D. and Mark Hyman, M.D. According to the CDC, about one in every 12 people has asthma, and the numbers are increasing every year. Asthma is a condition in which a person’s airway swells and becomes inflamed, resulting in difficulty breathing, shortness of breath and cough. There are many […]
Story Source Fundamental aspects of our clinical protocol for dealing with multiple sclerosis actually center upon re-building gut wall integrity. Multiple sclerosis, like other autoimmune conditions is a manifestation of lack of regulation of the immune system. We now understand that the integrity of the gut wall plays a fundamentally important role in keeping balance […]
DrPerlmutter.com As I have discussed on many occasions in this forum, the process of inflammation is a cornerstone of virtually any degenerative condition in the human experience. This includes diseases like cancer, diabetes, coronary artery disease, Alzheimer’s disease, Parkinson’s disease, stroke, arthritis, and so many more. So it’s really important that we take a step […]
This website contrasts diverse perspectives of the Gluten Syndrome, it’s best known subset, celiac disease, and related food reactivities. Please read Nine Crucial Points below before entering the rest of the site. Most gluten information is published by medical centers, support organizations or food vendors. A few websites and patient forums represent the largest laboratory of all, […]
Posted on Tue, Apr 22, 2014 @ 10:17 AM Patients with autoimmune diseases such as, rheumatoid arthritis, systemic lupus erythematosus, or Sjogren’s disease are typically given protocol-driven treatments with limited success because an acute care model is given to a chronic problem while the underlying causes are never investigated. The problem with this is everyone […]
Published: Apr 16, 2014 | Updated: Apr 17, 2014 By Nancy Walsh, Senior Staff Writer, MedPage Today Full Story Action Points Note that several studies have begun to implicate particular commensal pathogens as potentially etiologic in the development or perpetuation of rheumatoid arthritis. Be aware that no interventional trials, such as a trial of pathogen […]
For decades, “leaky gut syndrome” was passed off as quackery. But new research shows it is indeed real, and may be the cause of asthma, irritable bowel syndrome, arthritis, and more. Daniela Drake, M.D., M.B.A., is a former McKinsey & Co. consultant who is now a board-certified internist in private practice in Los Angeles. 03.27.14 […]
by Mark Hyman, MD YOUR DIGESTIVE SYSTEM may be making you fat. It’s hard to believe—but very true. I want to explain the bugs in your digestive tract, why they upset your gut’s immune system, and how they just might be behind those extra pounds. I have observed this phenomenon in hundreds of patients. Recently, […]
Short-Chain Fatty Acids Activate AMP-Activated Protein Kinase and Ameliorate Ethanol-Induced Intestinal Barrier Dysfunction in Caco-2 Cell Monolayers Elhaseen E. Elamin First published October 16, 2013, doi: 10.3945/jn.113.179549 J. Nutr. December 1, 2013 vol. 143 no. 12 1872-1881 Abstract Short-chain fatty acids (SCFAs) have been shown to promote intestinal barrier function, but their protective effects against […]
Manfred Lamprecht, PhD, PhD Adj. Professor Centre for Physiological Medicine Medical University of Graz Harrachgasse 21/II 8010 Graz, AUSTRIA +436641555528 / +433163809610 (FAX) manfred.lamprecht@medunigraz.at / www.medunigraz.at “Probiotic Supplementation Affects Markers of Intestinal Barrier, Oxidation, and Inflammation in Trained Men; A Randomized, Double-Blinded, Placebo-Controlled Trial,” J Int Soc Sports Nutr, 2012 Sep 20; 9(1):45. 49368 (11/2012) […]
Fasano A. Journal Clin Rev Allergy Immunol. 2012 Feb;42(1):71-8. doi: 10.1007/s12016-011-8291-x. Abstract Autoimmune diseases are characterized by tissue damage and loss of function due to an immune response that is directed against specific organs. This review is focused on the role of impaired intestinal barrier function on autoimmune pathogenesis. Together with the gut-associated lymphoid tissue […]
Effect of lactobacilli on paracellular permeability in the gut. Authors Ahrne S, et al. Journal Nutrients. 2011 Jan;3(1):104-17. doi: 10.3390/nu3010104. Epub 2011 Jan 12. Affiliation Abstract Paracellular permeability is determined by the complex structures of junctions that are located between the epithelial cells. Already in 1996, it was shown that the human probiotic strain Lactobacillus plantarum […]
De-Souza, Daurea A. MD Critical Care Medicine: May 2005 – Volume 33 – Issue 5 – pp 1125-1135 doi: 10.1097/01.CCM.0000162680.52397.97 Abstract Objective: This article provides a critical review of the evidence indicating that an increase in intestinal permeability is associated with the installation of bacteremia, sepsis, and the multiple organ failure syndrome and that glutamine […]
The Lancet. Volume 341, No. 8857, p1363–1365, 29 May 1993 Abstract Parenteral glutamine dipeptide improves nitrogen balance in postoperative patients on total parenteral nutrition (TPM). Animal studies show that the structure and function of the gut is preserved by glutamine. It is not known if this is the case in human beings. 20 patients admitted […]