Eur J Pain 2020 Jul 3. doi: 10.1002/ejp.1630. Online ahead of print. S F Farrell Abstract Background and objective: Mechanisms underpinning symptoms in non-traumatic neck pain (NTNP) and whiplash-associated disorder (WAD) are not comprehensively understood. There is emerging evidence of systemic inflammation in musculoskeletal pain conditions, including neck and back pain. The aim of this […]
Journal of the Royal Society Interface Maria Molinos, Catarina R. Almeida, Joana Caldeira, Carla Cunha, Raquel M. Gonçalves and Mário A. Barbosa Published:06 March 2015 https://doi.org/10.1098/rsif.2014.1191 Abstract Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a problem with a heavy economic burden, which has been increasing in prevalence as […]
Ann Rheum Dis. 2014 Sep;73(9):1683-8. doi: 10.1136/annrheumdis-2012-203143. Epub 2013 Jul 9. Evers AW Abstract OBJECTIVES: Both stressors and stress vulnerability factors together with immune and hypothalamus-pituitary-adrenal (HPA) axis activity components have been considered to contribute to disease fluctuations of chronic inflammatory diseases, such as rheumatoid arthritis (RA). The aim of the present study was to […]
Janos Feher, MD, PhD The Ocular Surface Volume 12, Issue 2 , Pages 134-145, April 2014 Abstract Previous studies showed comorbidity of some ocular, enteral, and affective symptoms comprising irritable eye syndrome. Aims of the present study were to learn more about the pathogenic mechanisms of this syndrome and to evaluate benefits of food supplements […]
Nat Rev Rheumatol. 2014 Jan;10(1):44-56. doi: 10.1038/nrrheum.2013.160. Epub 2013 Oct 29. Risbud MV, Shapiro IM. Abstract Degeneration of the intervertebral discs (IVDs) is a major contributor to back, neck and radicular pain. IVD degeneration is characterized by increases in levels of the proinflammatory cytokines TNF, IL-1α, IL-1β, IL-6 and IL-17 secreted by the IVD cells; […]
Curcumin: a new paradigm and therapeutic opportunity for the treatment of osteoarthritis: curcumin for osteoarthritis management Yves Henrotin Springerplus. 2013; 2: 56. Published online Feb 18, 2013. doi: 10.1186/2193-1801-2-56 Full Text Article Abstract The management of osteoarthritis represents a real challenge. This complex and multi-factorial disease evolves over decades and requires not only the alleviation […]