Interleukin-8 (IL-8)

22 Jan
2019
Inflammation, Interleukin-8 (IL-8)
By André Broussard, D.C.

Characterization of neuroinflammation and periphery-to-CNS inflammatory cross-talk in patients with disc herniation and degenerative disc disease

Brain, Behavior, and Immunity Volume 75, January 2019, Pages 60-71 Vinko Palada Highlights • Concentrations of IL-8 in CSF were significantly higher in LDH patients compared to DDD patients and controls. • In LDH patients there was a positive correlation of IL-8 concentrations between CSF and serum. • Elevated IL-8 in CSF was associated with […]

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06 Mar
2015
Disc, Disc Degeneration, Inflammation, Interleukin-1 beta, Interleukin-6 (IL-6), Interleukin-8 (IL-8), Musculoskeletal System, Tumor Necrosis Factor Alpha (TNFα)
By André Broussard, D.C.

Inflammation in intervertebral disc degeneration and regeneration – Full Text Article

Journal of the Royal Society Interface Maria Molinos, Catarina R. Almeida, Joana Caldeira, Carla Cunha, Raquel M. Gonçalves and Mário A. Barbosa Published:06 March 2015 https://doi.org/10.1098/rsif.2014.1191 Abstract Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a problem with a heavy economic burden, which has been increasing in prevalence as […]

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02 Sep
2014
Immune System, Inflammation, Interleukin-1 beta, Interleukin-6 (IL-6), Interleukin-8 (IL-8), Psychiatric, Rheumatoid Arthritis, Stress, Tumor Necrosis Factor Alpha (TNFα)
By André Broussard, D.C.

Does stress affect the joints? Daily stressors, stress vulnerability, immune and HPA axis activity, and short-term disease and symptom fluctuations in rheumatoid arthritis

Ann Rheum Dis. 2014 Sep;73(9):1683-8. doi: 10.1136/annrheumdis-2012-203143. Epub 2013 Jul 9. Evers AW Abstract OBJECTIVES: Both stressors and stress vulnerability factors together with immune and hypothalamus-pituitary-adrenal (HPA) axis activity components have been considered to contribute to disease fluctuations of chronic inflammatory diseases, such as rheumatoid arthritis (RA). The aim of the present study was to […]

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21 Jan
2013
Disc, Disc Degeneration, Disc Herniation, Interleukin-1 beta, Interleukin-6 (IL-6), Interleukin-8 (IL-8), Lumbar Spine & Low Back Pain, Matrix Metalloproteinase, Musculoskeletal System, Sciatica
By André Broussard, D.C.

Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain

Global Spine J 2013; 03(03): 175-184 Karin Wuertz Abstract Although degeneration of the intervertebral disk has historically been described as a misbalance between anabolic and catabolic factors, the role of inflammatory mediators has long been neglected. However, past research clearly indicates that inflammatory mediators such as interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor-α are […]

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19 Aug
2010
Inflammation, Interleukin-1 beta, Interleukin-6 (IL-6), Interleukin-8 (IL-8), Low Back Pain Risk Factors, Lumbar Spine & Low Back Pain, Tumor Necrosis Factor Alpha (TNFα)
By André Broussard, D.C.

Pro-inflammatory cytokines expression increases following low-and high-magnitude cyclic loading of lumbar ligaments

Pro-inflammatory cytokines expression increases following low-and high-magnitude cyclic loading of lumbar ligaments D’Ambrosia P, et al. Eur Spine J. 2010 Aug;19(8):1330-9. doi: 10.1007/s00586-010-1371-4. Epub 2010 Mar 25. Abstract Repetitive or overuse disorders of the lumbar spine affect the lives of workers and athletes. We hypothesize that repetitive anterior lumbar flexion-extension under low or high load […]

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