Inflammation

Exploration of the Inter-Relationships Between Obesity, Physical Inactivity, Inflammation, and Low Back Pain

Hashem, Lukas E., BSc Spine: September 1, 2018 – Volume 43 – Issue 17 – p 1218-1224 doi: 10.1097/BRS.0000000000002582 Study Design. Retrospective analysis wherein 103 patients were considered, and 76 patients were included: 49 were classified as chronic non-specific low back pain (CNSLBP) (Study group) and 27 had identifiable cases of specific chronic low back pain (LBP) (Control […]

The Pathogenesis of Diabetes Mellitus by Oxidative Stress and Inflammation: Its Inhibition by Berberine – Full Text Article

Front. Pharmacol., 27 July 2018 | https://doi.org/10.3389/fphar.2018.00782 Xueling Ma A substantial knowledge on the pathogenesis of diabetes mellitus (DM) by oxidative stress and inflammation is available. Berberine is a biologically active botanical that can combat oxidative stress and inflammation and thus ameliorate DM, especially type 2 DM. This article describes the potential of berberine against […]

Adherence to Mediterranean diet, high-sensitive C-reactive protein, and severity of coronary artery disease: Contemporary data from the INTERCATH cohort

Atherosclerosis August 2018 Volume 275, Pages 256–261 Christoph Waldeyer Highlights •The guidelines strongly recommend a healthy diet as a cornerstone of cardiovascular disease prevention. •An association with Mediterranean diet (MD) has been shown for different vascular beds. •There are no multivariate data regarding Mediterranean diet and the extent of coronary artery disease (CAD). •The present […]

Osteoarthritis Should Be Viewed As “Heart Disease” Of The Joints – Video

June 26, 2018 David Seaman DC At first glance, the title of this blog may seem like a preposterous notion; however, it is a fact. Years ago, osteoarthritis (OA) was misperceived to be a wear-and-tear condition of joints, a myth that is still perpetuated today…however, we now know that OA is actually a chronic inflammatory […]

Study identifies a link between antidepressant treatment resistance and inflammation

Woodruff Health Sciences Center | June 7, 2018 Researchers at Emory University have found that depressed patients who have not responded to multiple antidepressants exhibit evidence of increased inflammation. Findings were recently published online in the journal, Psychoneuroendocrinology. The study shows that antidepressant treatment resistance is associated with increased inflammatory markers in patients with depression. […]

Electroacupuncture Promotes Central Nervous System‐Dependent Release of Mesenchymal Stem Cells – Full Text Article

Tatiana E. Salazar Stem Cells 2017;35:1303–1315 Abstract Electroacupuncture (EA) performed in rats and humans using limb acupuncture sites, LI‐4 and LI‐11, and GV‐14 and GV‐20 (humans) and Bai‐hui (rats) increased functional connectivity between the anterior hypothalamus and the amygdala and mobilized mesenchymal stem cells (MSCs) into the systemic circulation. In human subjects, the source of […]

Effects of Transcutaneous Electrical Nerve Stimulation on Proinflammatory Cytokines: Systematic Review and Meta-Analysis – Full Text Article

Mediators Inflamm. 2018; 2018: 1094352. Published online 2018 Apr 2. doi: 10.1155/2018/1094352 PMCID: PMC5901481 PMID: 29805310 Tábata Cristina do Carmo Almeida,corresponding author 1 Francisco Winter dos Santos Figueiredo, 1 Valter Cordeiro Barbosa Filho, 2 Luiz Carlos de Abreu, 3 Fernando Luiz Affonso Fonseca, 4 and Fernando Adami 1 Abstract The mechanism of pain reduction involves […]

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

Science. 2018 Mar 23;359(6382):1376-1383. doi: 10.1126/science.aar3318. Epub 2018 Mar 8. Thaiss CA. Abstract Obesity, diabetes, and related manifestations are associated with an enhanced, but poorly understood, risk for mucosal infection and systemic inflammation. Here, we show in mouse models of obesity and diabetes that hyperglycemia drives intestinal barrier permeability, through GLUT2-dependent transcriptional reprogramming of intestinal […]

Low-calorie sweeteners may promote metabolic syndrome

MARCH 19, 2018 Top News in Internal Medicine Healthline/Medical News Today New data—presented at the annual meeting of the Endocrine Society, held in Chicago, IL—suggest that consuming low-calorie sweeteners could put people at risk of metabolic syndrome. Around 34% of adults in the United States have metabolic syndome—the umbrella term for: high blood pressure; high blood sugar; […]

Effects of long-term consumption of broccoli sprouts on inflammatory markers in overweight subjects

Clin Nutr. 2018 Mar 13. pii: S0261-5614(18)30118-3. doi: 10.1016/j.clnu.2018.03.006. [Epub ahead of print] López-Chillón MT Abstract BACKGROUND & AIMS: Broccoli sprouts represent an interesting choice of healthy food product as they are rich in glucosinolates and their cognate bioactive metabolites, isothiocyanates able to counteract the negative effects of diverse pathologies. As obesity is linked to […]

The effects of folate supplementation on glucose metabolism and risk of type 2 diabetes: A systematic review and meta-analysis of randomized controlled trials

Annals of Epidemiology — | February 26, 2018 Zhao JV, et al. – Folate, which reduces homocysteine, is promising for the prevention and treatment of diabetes. Previous meta-analysis of 3 trials suggested folate might lower hemoglobin A1c (HbA1c). In this current updated systematic review and meta-analysis of placebo-controlled randomized trials, a potential benefit of folate […]

Serum Homocysteine Higher in Acne Patients

December 22, 2017 Authors say measurement of serum homocysteine may be important for patient management THURSDAY, Dec. 14, 2017 (HealthDay News) — Acne patients have higher levels of serum homocysteine (HCY), according to a study published online Nov. 21 in the Journal of Cosmetic Dermatology. Hao Jiang, M.D., from the First Affiliated Hospital of Guangxi University […]

Inflammation and its resolution and the musculoskeletal system

J Orthop Translat. 2017 Jul;10:52-67. doi: 10.1016/j.jot.2017.05.007. Epub 2017 Jun 3. Gallo J1, Raska M2, Kriegova E2, Goodman SB3. Abstract Inflammation, an essential tissue response to extrinsic/intrinsic damage, is a very dynamic process in terms of complexity and extension of cellular and metabolic involvement. The aim of the inflammatory response is to eliminate the pathogenic […]

Reducing inflammation without lowering cholesterol cuts risk of cardiovascular events

Inflammatory hypothesis confirmed: Landmark randomized clinical trial of high-risk patients finds that a drug targeting inflammation reduced risk of major adverse cardiovascular events Date: August 28, 2017 Source: Brigham and Women’s Hospital Summary: Investigators have announced results of a clinical trial culminating from 25 years of cardiovascular research work. The team reports a significant reduction […]

Effect of Moderate-Intensity Exercise on Inflammatory Markers Among Postmenopausal Women

J Phys Act Health. 2017 Jun;14(6):479-485. doi: 10.1123/jpah.2016-0319. Epub 2017 Mar 2. Chagas EFB, Bonfim MR, Turi BC, Brondino NCM, Monteiro HL. Abstract BACKGROUND: Declines in ovarian function in postmenopausal women may contribute to increase inflammatory cytokines, which can lead to chronic diseases. However, studies have shown that exercise interventions are important to manage inflammatory conditions. Thus, the objective of […]

Chlamydia and Heart Disease

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. How secure should you feel if your doctor tells you that your cholesterol levels are normal? Are you immune to heart disease just because you have been informed you have normal cholesterol levels? If you have been a reader of my weekly articles for any length of time, you […]

Meditation and yoga can ‘reverse’ DNA reactions which cause stress, new study suggests

Date: June 15, 2017 Source: Coventry University Summary: Mind-body interventions (MBIs) such as meditation, yoga and Tai Chi don’t simply relax us; they can ‘reverse’ the molecular reactions in our DNA which cause ill-health and depression, according to a study. Mind-body interventions (MBIs) such as meditation, yoga and Tai Chi don’t simply relax us; they […]

Association Between Body Mass Index, C-Reactive Protein Levels, and Melanoma Patient Outcomes

May 15, 2017 Journal of Investigative Dermatology TAKE-HOME MESSAGE This retrospective analysis of 1804 melanoma patients from 1998 to 2008 investigated the effect of body mass index (BMI) and C-reactive protein levels on melanoma outcomes. Increased BMI was associated with lower overall and melanoma-specific survival. Increased BMI was also associated with lower overall and melanoma-specific […]

Changes in biochemical markers following spinal manipulation-a systematic review and meta-analysis

Musculoskeletal Science & Practice June 2017  Volume 29, Pages 120–131 Kesava Kovanur-Sampath, M.Ost Highlights •Various biochemical markers such as substance-P, neurotensin, interleukins and cortisol modulate pain and inflammation. •Spinal manipulation increases substance-P, neurotensin, oxytocin and can alter various biochemical marker. •Spinal manipulation therefore may play an important role in pain and or inflammatory disorders. •Future RCTs […]

Chlamydia and Heart Disease

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. How secure should you feel if your doctor tells you that your cholesterol levels are normal Are you immune to heart disease just because you have been informed you have normal cholesterol levels? If you have been a reader of my weekly articles for any length of time, you […]