Inflammation

Mediterranean diet may decrease pain associated with obesity

Published: Friday 24 February 2017 Eating a Mediterranean diet could decrease the chances an overweight person will experience regular pain, new research suggests. A well-established connection between body weight and chronic pain might be explained by inflammation in the body, and the study points to anti-inflammatory foods including fish, nuts and beans as a key […]

What may be lurking at the root of psoriasis?

Michael Jurgelewicz, DC, DACBN, DCBCN Psoriasis is an inflammatory skin condition that is characterized by itchy, scaly skin plaques. The exact cause of psoriasis is unknown; however, more and more evidence suggests that the immune system can be a culprit when it is chronically stimulated, causing an overproduction of cytokines, which maintains an inflammatory environment. […]

Mindfulness meditation lowers stress hormone and decreases inflammation in body, scientists find

Sarah Knapton 24 JANUARY 2017 Mindfulness meditation, the practice of paying more attention to the present moment, helps lower stress hormones and decreases inflammation in the body, scientists have proven for the first time. The training has been growing in popularity in recent years, with the NHS recommending mindfulness as a way to reduce stress and […]

Exercise …20 minutes can act as anti-inflammatory

One moderate exercise session has a cellular response that may help suppress inflammation in the body Date: January 12, 2017 Source: University of California – San Diego Summary: It’s well know that regular physical activity has health benefits, including weight control, strengthening the heart, bones and muscles and reducing the risk of certain diseases. Recently, […]

Study: Running actually lowers inflammation in knee joints

Brigham Young University Health News, 12/12/2016 Running may also slow the process that leads to osteoarthritis. New research from BYU exercise science professors finds that pro–inflammatory molecules actually go down in the knee joint after running. In other words, it appears running can reduce joint inflammation. “It flies in the face of intuition,” said study […]

Ketogenic Diets and Pain (Full Text)

J Child Neurol. Author manuscript; available in PMC 2014 Aug 7. Published in final edited form as: J Child Neurol. 2013 Aug; 28(8): 993–1001. Published online 2013 May 16. doi: 10.1177/0883073813487595 PMCID: PMC4124736 NIHMSID: NIHMS506894 Susan A. Masino, Ph.D.* and David N. Ruskin, Ph.D. Abstract Ketogenic diets are well-established as a successful anticonvulsant therapy. Based […]

Obesity May Increase Cognitive Decline via Inflammation

Liam Davenport October 24, 2016 Being overweight or obese leads to clinically meaningful increases in the rate of cognitive decline in association with changes in inflammatory markers in the blood, a new analysis of longitudinal data suggests. The results, which indicate that an increased body mass index (BMI) may accelerate cognitive decline by several months […]

Functions of Coenzyme Q10 Supplementation on Liver Enzymes, Markers of Systemic Inflammation, and Adipokines in Patients Affected by Nonalcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial.

J Am Coll Nutr. 2016 May-Jun;35(4):346-53. doi: 10.1080/07315724.2015.1021057. Epub 2015 Jul 9. Farsi F1, Mohammadshahi M1, Alavinejad P2, Rezazadeh A3, Zarei M4, Engali KA5. Abstract BACKGROUND: Nonalcoholic fatty liver disease (NAFLD) is a chronic liver disorder related to inflammation. Coenzyme Q10 (CoQ10) is a natural compound that has recently been considered as an anti-inflammatory factor. […]

Association Between the Plasma Levels of Mediators of Inflammation With Pain and Disability in the Elderly With Acute Low Back Pain: Data From the Back Complaints in the Elders (BACE)-Brazil Study

Spine: February 2016 – Volume 41 – Issue 3 – p 197–203 doi: 10.1097/BRS.0000000000001214 de Queiroz, Bárbara Zille PhD Abstract Study Design. Cross-sectional study with subsample of elderly women with acute low back pain (LBP), from Back Complaints in the Elders-Brazil (BACE-Brazil) Objective. To investigate the association between plasma levels of mediators of inflammation (interleukin-1 […]

Elevated levels of tumor necrosis factor-α and TNFR1 in recurrent herniated lumbar discs correlate with chronicity of postoperative sciatic pain

The Spine Journal Volume 16, Issue 2, February 2016, Pages 243–251 Pablo Andrade, MD, PhD Abstract Background Context Sciatica is a condition characterized by radicular pain that can be secondary to a lumbar disc herniation (LDH). More than 10% of patients report persistent pain after surgery. The underlying mechanisms of postoperative sciatica remain unclear. There […]

Garlic and heart disease

The Journal of Nutrition, 01/29/2016 Varshney R, et al. Researchers sought to assess the effects of garlic supplements on hypertension, hypercholesterolemia, C–reactive protein (CRP), pulse wave velocity (PWV), and coronary artery calcium (CAC), as well as available data on adverse reactions. They found that garlic supplementation may offer cardiovascular protection. Methods Researchers searched PubMed for […]

The neurons in our gut help the immune system keep inflammation in check

Date: January 22, 2016 Source: Rockefeller University Summary: The immune system must protect against potential infections, but over-vigilant reactions can cause problems. New research shows that neurons in the intestine send signals to immune cells to curb inflammation. The immune system exercises constant vigilance to protect the body from external threats–including what we eat and […]

New National Guidelines Discuss Measuring Inflammatory Biomarkers to Identify Increased Stroke Risk

Posted on January 21, 2015 by Cleveland HeartLab The American Heart Association/American Stroke Association (AHA/ASA) just published new guidelines for the primary prevention of stroke that acknowledge the relationship between inflammation and various stages of the atherogenic process including initiation, progression, and stability of atherosclerotic lesions.  They reference a number of studies that show associations […]

Low Levels of Vitamin D Linked to Inflammation

Posted on January 21, 2015 by Cleveland HeartLab Investigators from Ireland have published results of an observational study (n=957) conducted in hypertensive adults >60 years of age in the Journal of Clinical Endocrinology and Metabolism which clearly links low levels of 25-hydroxy vitamin D [25(OH)D] with several markers of inflammation, including high-sensitivity C-reactive protein (hsCRP).Inflammatory […]

Inflammation Tied to Bone Marrow Lesions in Knee OA

01.20.2016 Results may facilitate development of new treatment strategies by Wayne Kuznar Contributing Writer Systemic inflammation was linked with bone marrow lesion scores and pain in patients with knee osteoarthritis (OA), researchers from Australia and China reported. Serum high sensitivity-C-reactive protein (hs-CRP) was associated with the presence of knee bone marrow lesions and knee pain, […]

Low-level laser therapy regulates microglial function through Src-mediated signaling pathways: implications for neurodegenerative diseases

Journal of Neuroinflammation 2012, 9:219 Sheng Song Abstract Background Activated microglial cells are an important pathological component in brains of patients with neurodegenerative diseases. The purpose of this study was to investigate the effect of He-Ne (632.8 nm, 64.6 mW/cm2) low-level laser therapy (LLLT), a non-damaging physical therapy, on activated microglia, and the subsequent signaling events of […]

New approach to diagnosing low back pain, revealed by clinical study

Date: January 7, 2016 Source: North Shore-Long Island Jewish (LIJ) Health System Summary: A new, personalized approach to diagnosing low back pain has been discovered by researchers. Low back pain is the second most common cause of physician visits in the US and contributes to an estimated $100 billion in US costs per year, making […]

How the Mediterranean diet and some of its components modulate inflammatory pathways in arthritis

Swiss Medical Weekly, 11/13/2015 Oliviero F, et al. Although some aspects concerning the mechanisms of action through which the Mediterranean diet pattern exerts its beneficial effects remain to be elucidated, arthritis patients may potentially benefit from it in view of their increased cardiovascular risk and the treatment they require which may have side effects Arthritis […]

Fish oil supplementation does not lower C-reactive protein or interleukin-6 levels in healthy adults

Journal of Internal Medicine, 11/03/2015 Muldoon MF, et al. The n–3 polyunsaturated fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) may prevent a range of chronic conditions through anti–inflammatory actions. However, as clinical trials using these fatty acids for primary prevention are yet unavailable, their putative role in disease prevention rests, in part, on […]

Study Associates Chronic Dysglycemia (HbA1c ≥ 5.8%) with Inflammation, Endothelial Dysfunction, and Higher Cardiovascular Event Rates post STEMI

Posted on November 9, 2015 by Cleveland HeartLab Many prevention specialists believe that we are not diagnosing diabetes early enough if we wait for hemoglobin A1c(HbA1c) levels to reach ≥ 6.5%.  Filepe Moura and colleagues sought to find out if there was a relationship between HbA1c  levels in non-diabetic ST-elevation myocardial infarction (STEMI) patients and […]