Diana Swift October 07, 2015 Findings from a Danish population-based study suggest a twofold increased relative risk for central demyelinating diseases in patients with inflammatory bowel disease (IBD) who receive tumor necrosis factor (TNF) inhibitors. “If true, the observed association could either be attributed to the unmasking of a latent demyelinating disease or to the […]
Open Heart 2015;2: doi:10.1136/openhrt-2015-000273 Editorial It is time to stop counting calories, and time instead to promote dietary changes that substantially and rapidly reduce cardiovascular morbidity and mortality Aseem Malhotra1, James J DiNicolantonio3and Simon Capewell Most heart attacks and ischaemic strokes are caused by complicated atheroma usually compounded by thrombosis suddenly reducing blood flow in […]
Megan Brooks September 01, 2015 Nine potentially modifiable risk factors may explain two thirds of Alzheimer’s disease (AD) cases globally, according to a comprehensive meta-analysis of published studies. Risk factors include obesity, carotid artery narrowing, low educational achievement, hyperhomocysteine, depression, hypertension, frailty, current smoking, and type 2 diabetes (diabetes only in Asian populations). According to […]
Scientists show how sugar-derived molecules can weaken infection-fighting antimicrobial beta-defensin peptides Date: August 6, 2015 Source: Case Western Reserve University Summary: Scientists may have uncovered a molecular mechanism that sets into motion dangerous infection in the feet and hands often occurring with uncontrolled diabetes. It appears that high blood sugar unleashes destructive molecules that interfere with […]
Date: August 17, 2015 Research has shown that a regular dose of aspirin reduces the long-term risk of cancer in those who are overweight in an international study of people with a family history of the disease. The study, conducted by researchers at Newcastle University and the University of Leeds, UK, is published in the […]
Date: August 7, 2015 Source: ILSI Europe Summary: An unresolved inflammatory response is likely to be involved from the early stages of disease development, scientists say. Controlling inflammation is crucial to human health and a key future preventative and therapeutic target. In a recent article, a coalition of experts explains how nutrition influences inflammatory processes […]
August 5, 2015 Scientists have cracked the secret of why some people live a healthy and physically independent life over the age of 100. For the first time, a team of experts from Newcastle University’s Institute for Ageing and Keio University School of Medicine, Tokyo, explored which biological and pathological processes may be the most […]
Arthritis & Rheumatism 07/21/2015 Attur M, et al. Inflammatory mediators, such as PGE2 and IL–1β, are produced by osteoarthritic joint tissues, where they may contribute to disease pathogenesis. The authors examined whether inflammation, reflected in plasma and peripheral blood leukocytes (PBLs) reflected presence of osteoarthritis (OA), progression or symptoms in patients with symptomatic knee osteoarthritis […]
By James P. Meschino, DC, MS A study published in the July 2013 issue of the American Journal of Clinical Nutrition provides additional evidence suggesting higher nutritional status of certain B vitamins may be important in the prevention of age-related macular degeneration (AMD), which is the leading cause of vision loss in people over 55 […]
A few months ago a story in The New York Times revealed the newly discovered importance of high sensitivity C-reactive protein (CRP). Apparently, a drug company-sponsored study showed that people who had high CRP levels had fewer heart attacks and strokes when taking statins (cholesterol-lowering drugs). Suddenly, the whole medical community is buzzing about the […]
Lupus. 2015 Apr;24(4-5):483-9. doi: 10.1177/0961203314558676. A randomized double-blind placebo-controlled study adding high dose vitamin D to analgesic regimens in patients with musculoskeletal pain. Gendelman O1, Itzhaki D2, Makarov S3, Bennun M3, Amital H4. BACKGROUND: The current mode of therapy for many patients with musculoskeletal pain is unsatisfactory. PURPOSE: We aimed to assess the impact of […]
4/10/15 by Wayne Kuznar Contributing Writer In patients with axial spondyloarthritis (SpA), increased serum alkaline phosphatase (ALP) levels not only reflect high disease activity but also low bone mineral density (BMD) and structural damage, according to a cross-sectional study by South Korean researchers. The need for biomarkers that reflect both disease activity and bone metabolism […]
MAGNA: Fish-Oil Supplementation May Lower Thrombosis Risk Deborah Brauser March 17, 2015 SAN DIEGO, CA — Although lively debate has raged about whether fish-oil supplementation (FOS) really is beneficial for preventing cardiovascular events, new research suggests that it may reduce the “overall atherothrombotic risk profile” in patients with suspected CAD[1]. Results from the Multi-Analyte, Thrombogenic, and Genetic Markers […]
The American Journal of Gastroenterology 110, 444-454 (March 2015) | doi:10.1038/ajg.2015.6 TAKE-HOME MESSAGE In this meta-analysis, researchers evaluated the diagnostic potential of biomarkers for irritable bowel disease (IBD) and irritable bowel syndrome (IBS), finding that biomarkers did not differentiate patients with IBS from controls. The risk for IBD was ≤1% with C-reactive protein ≤0.5 and […]
Journal of the Royal Society Interface Maria Molinos, Catarina R. Almeida, Joana Caldeira, Carla Cunha, Raquel M. Gonçalves and Mário A. Barbosa Published:06 March 2015 https://doi.org/10.1098/rsif.2014.1191 Abstract Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a problem with a heavy economic burden, which has been increasing in prevalence as […]
The Many Health Benefits of Cinnamon Cinnamon is a powerful spice that has been used medicinally around the world for thousands of years. It is still used daily in many cultures because of its widespread health benefits, not to mention its distinctly sweet, warming taste and ease of use in recipes. According to researchers, out of twenty-six […]
Date: February 16, 2015 Source: Yale University Summary: Researchers have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer’s disease. In their study, published in the Feb. 16 online issue ofNature […]
Effects of Nuclear Factor Kappa B Signaling Pathway in Human Intervertebral Disc Degeneration Zhongyi, Sun PhD; Sai, Zhao PhD; Chao, Liu PhD; Jiwei, Tian PhD Spine 15 February 2015 Vol. 40 – Issue 4: p 224–232 Abstract Study Design. IL-1β (interleukin-1β) can activate human nucleus pulposus cells with or without nuclear factor kappa B (NF-κB) […]