Inflammation

Chocolate and the brain

Neurobiological impact of cocoa flavanols on cognition and behavior Sokolov AN Neurosci Biobehav Rev. 2013 Jun 26. pii: S0149-7634(13)00168-1 Abstract Cocoa products and chocolate have recently been recognized as a rich source of flavonoids, mainly flavanols, potent antioxidant and anti-inflammatory agents with established benefits for cardiovascular health but largely unproven effects on neurocognition and behavior. […]

Exercise May Lower C-Reactive Protein

Published: Nov 8, 2013 | Updated: Nov 8, 2013 By Ed Susman , Contributing Writer, MedPage Today Full Story:  http://www.medpagetoday.com/MeetingCoverage/WCIR/42804 Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. There is a […]

Coenzyme Q10 Supplementation Enhances Antioxidant Activity and Lowers Inflammation in Patients with Coronary Artery Disease on Statin Drug Therapy

Effects of coenzyme Q10 supplementation (300 mg/day) on antioxidation and anti-inflammation in coronary artery disease patients during statins therapy A randomized, placebo-controlled trial Lee BJ, Tseng YF, Yen CH, Lin PT. Abstract BACKGROUND: High oxidative stress and chronic inflammation can contribute to the pathogenesis of coronary artery disease (CAD). Coenzyme Q10 is an endogenous lipid-soluble […]

Association between erythrocyte n-3 polyunsaturated fatty acids and biomarkers of inflammation and oxidative stress in patients with and without depression

Baek D, Park Y. Abstract Associations between n-3 polyunsaturated fatty acids (PUFAs), inflammation, oxidative stress and the risk of depression have been suggested. We hypothesize that erythrocyte n-3 PUFAs are inversely associated with biomarkers for inflammation and oxidative stress in Koreans with and without depression. Study participants comprised 80 cases diagnosed with depression based on […]

Role of cytokines in intervertebral disc degeneration: pain and disc content

Role of cytokines in intervertebral disc degeneration: pain and disc content Risbud MV,et al. Show allJournal Nat Rev Rheumatol. 2013 Oct 29. doi: 10.1038/nrrheum.2013.160. [Epub ahead of print] Affiliation Department of Orthopaedic Surgery, Jefferson Medical College, 1025 Walnut Street, 511 College Building, Philadelphia, PA 19107, USA. Abstract Degeneration of the intervertebral discs (IVDs) is a […]

Associations of Cytokine Concentrations With Key Osteopathic Lesions and Clinical Outcomes in Patients With Nonspecific Chronic Low Back Pain

Results From the OSTEOPATHIC Trial John C. Licciardone, DO, MS, MBA Abstract Context: Little is known about the role that cytokines play in osteopathic manual treatment (OMT) of patients with chronic low back pain (LBP). Objective: To measure the baseline concentrations of interleukin (IL)-1β, IL-6, IL-8, IL-10, and tumor necrosis factor (TNF)-α in patients with chronic LBP; […]

Role of cytokines in intervertebral disc degeneration: pain and disc content

Nat Rev Rheumatol. 2014 Jan;10(1):44-56. doi: 10.1038/nrrheum.2013.160. Epub 2013 Oct 29. Risbud MV, Shapiro IM. Abstract Degeneration of the intervertebral discs (IVDs) is a major contributor to back, neck and radicular pain. IVD degeneration is characterized by increases in levels of the proinflammatory cytokines TNF, IL-1α, IL-1β, IL-6 and IL-17 secreted by the IVD cells; […]

Role of Adipokines in the Modulation of T Cells Function

Procaccini C,et al. Front Immunol. 2013 Oct 18;4:332. Abstract The field that links immunity and metabolism is rapidly expanding. Apparently non-immunological disorders such as obesity and type 2 diabetes have been linked to immune dysregulation, suggesting that metabolic alterations can be induced by or be consequence of an altered self-immune tolerance. In this context, adipose […]

Mood-Gut Link Seen in IBS

Published: Oct 14, 2013 | Updated: Oct 16, 2013 By Charles Bankhead Full Story:   http://www.medpagetoday.com/MeetingCoverage/ACG/42247 Action Points Note that this study was published as an abstract and presented at a conference. These data and conclusions should be considered to be preliminary until published in a peer-reviewed journal. SAN DIEGO — Psychological comorbidity had a significant […]

Markers of Systemic Inflammation in Psoriasis

A Systematic Review and Meta-analysis E.A. Dowlatshahi The British Journal of Dermatology. 2013;169(2):266-282. Abstract Studies investigating systemic inflammation in psoriasis use different serum markers and report discrepant results. We set out to determine whether systemic inflammation is elevated in patients with psoriasis compared with healthy controls, and to measure the extent of this elevation, by […]

Increased inflammatory markers point toward higher risk for hip fracture

Full Story:  Endocrinology Today BALTIMORE — Higher concentrations of inflammatory factors were associated with higher risk for hip fracture, according to study results presented here. “Inflammatory burden may be an important biological factor in fracture etiology, particularly for hip fractures, and now we are seeing this consistency across studies,” Kamil E. Barbour, PhD, MPH, MS, […]

Fish Oil Shows Benefits in RA

Published: Oct 2, 2013 | Updated: Oct 2, 2013 By Nancy Walsh Full Story:  http://www.medpagetoday.com/Rheumatology/Arthritis/42007 Action Points Note that this small randomized trial demonstrated that fish oil, in addition to standard therapy, increased the remission rate in new-onset rheumatoid arthritis. Be aware that larger studies in other populations will be needed to validate the use […]

Infographic for Rheumatoid Arthritis

http://www.medpagetoday.com/resource-center/rheumatoid-arthritis/Infographic/i/38228  

The Silent Bacteria and Atherosclerosis

Ronald Grisanti D.C., D.A.B.C.O., D.A.C.B.N., M.S. Is it possible that a species of bacteria that commonly causes colds, sinus infections, bronchitis, asthma or pneumonia can also be a silent cause of atherosclerosis? Atherosclerosis (also known as arteriosclerotic vascular disease or ASVD) is a specific form of arteriosclerosis in which an artery wall thickens. Many people […]

Relations of C-Reactive Protein and Obesity to the Prevalence and the Odds of Reporting Low Back Pain

Presented to the School of Health and Rehabilitations Sciences Grand Rounds, The Ohio State University, June 1, 2011, Columbus, OH and the American Physical Therapy Association, February 10, 2011, New Orleans, LA. Archives of Physical Medicine and Rehabilitation Volume 94, Issue 4 , Pages 745-752, April 2013 Matthew S. Briggs, DPT Abstract Objective To assess […]

Are Grains Destroying Our Brains?

Dr. Perlmutter, a leader in the emerging field of functional neurology, contends that our grain-heavy diets are a major etiologic factor in Alzheimer’s disease and other forms of dementia—diseases that mainstream medicine view as an inevitable consequence of genetics and age.

Cytokine Levels Tied to Unhealthy Aging

…”elevated levels of interleukin-6 (IL-6) were associated with unhealthy aging and a higher risk of cardiovascular events and death…”

Betaine Supplementation Decreases Plasma Homocysteine Levels in Healthy Adults

Betaine Supplementation Decreases Plasma Homocysteine Levels in Healthy Adults Keywords: HOMOCYSTEINE – Betaine Reference: “Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis,” McRae MP, J Chiropr Med, 2013 March; 12(1): 20-5. (Address: Associate Professor, Department of Basic Science, National University of Health Sciences, Lombard, IL, USA). Summary: In a meta-analysis of 5 […]

Homocysteine, Depression and Cognitive Function in Older Adults

So what can we recommend to keep the homocysteine level low?

Omega-3 fatty acid, DHA switches off cellular inflammation to slash chronic disease risk

Monday, August 12, 2013 by: John Phillip (NaturalNews) Medical researchers have become increasingly aware that many chronic illnesses ranging from cardiovascular disease and cancer to dementia and arthritis are fueled by excess cellular inflammation. Systemic inflammation creates an environment that is conducive to genetic alterations and can lead to immune system dysfunction as macrophages, normally […]