Published: Nov 1, 2013 | Updated: Nov 1, 2013 By Cole Petrochko, Staff Writer, MedPage Today Full Story: http://www.medpagetoday.com/Geriatrics/GeneralGeriatrics/42648 Action Points A characteristic of biological aging is the non-enzymatic glycation of long-lasting proteins, such as collagen, which weakens collagen’s biomechanical properties and leads to increased bone matrix stiffening and fragility. This study shows that increasing […]
The Study: Polypharmacy correlates with increased risk for hip fracture in the elderly: a population-based study. The Facts: a. Hip fracture is an important public health issue. b. The authors looked at the insurance claims of 2328 elderly patients in Taiwan who had previously suffered a hip fracture. c. They sought to see if hip […]
Douglas C. Bauer, M.D. N Engl J Med 2013; 369:1537-1543October 17, 2013DOI: 10.1056/NEJMcp1210380 This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author’s clinical recommendations. A 62-year-old healthy woman presents for […]
Published: May 17, 2013 | Updated: May 18, 2013 By Kristina Fiore , Staff Writer, MedPage Today Action Points In this prospective case-cohort study of hip fractures, there was an increased risk of hip fracture in subjects in the lowest compared to the highest quartile of serum 25-hydroxyvitamin D level. The association was stronger in […]
Published: Apr 12, 2013 By Nancy Walsh , Staff Writer, MedPage Today Action Points Older women with low abdominal fat stores were at substantially higher risk for fractures, particularly of the vertebrae. Note that fracture risk among both women and men was significantly greater with older age, previous fracture, history of falls, and lower bone […]
Osteoporos Int. 2008 Jan;19(1):65-9. Epub 2007 Sep 14. Flattening of sagittal spinal curvature as a predictor of vertebral fracture. Kobayashi T Abstract In a 12-year prospective study of 100 adult volunteers, incident vertebral fractures were analyzed for potential predictors. Decreased sagittal spinal curvature and pre-existing fractures were identified as independent predictors. The risk of vertebral […]