A Randomized Clinical Trial Xingzhong Jin, MD JAMA March 8, 2016, Vol 315, No. 10 Importance Observational studies suggest that vitamin D supplementation is associated with benefits for knee osteoarthritis, but current trial evidence is contradictory. Objective To compare the effects of vitamin D supplementation vs placebo on knee pain and knee cartilage volume in […]
Calamia V, et al. Journal Sci Rep. 2014 Jun 10;4:5069. doi: 10.1038/srep05069. Affiliation Abstract Osteoarthritis (OA) is the most common age-related rheumatic disease. Chondrocytes play a primary role in mediating cartilage destruction and extracellular matrix (ECM) breakdown, which are main features of the OA joint. Quantitative proteomics technologies are demonstrating a very interesting power for studying […]