Disc Degeneration

03 Jan
2014
Disc, Disc Degeneration
By André Broussard, D.C.

Acute mechanical injury of the human intervertebral disc: link to degeneration and pain

Citation:  Alkhatib B, Rosenzweig DH, Krock E, Roughley PJ, Beckman L, Steffen T, Weber MH, Ouellet JA, Haglund L. Eur. Cell Mater. 2014; 28: 98-111. Affiliation:  McGill University Health Centre, Department of Surgery, Montreal General Hospital, Room C9.173, 1650 Cedar Ave, Montreal, QC H3G 1A4, Canada.lisbet.haglund@mcgill.ca. (Copyright © 2014) PMID:  25214017 Abstract Excessive mechanical loading or acute trauma […]

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03 Aug
2013
Disc, Disc Degeneration, Lumbar Spine & Low Back Pain, Lumbar Spondylolisthesis, Musculoskeletal System
By André Broussard, D.C.

The relationship between sagittal spinopelvic parameters and the degree of lumbar intervertebral disc degeneration in young adult patients with low-grade spondylolytic spondylolisthesis

Bone Joint J. 2013 Sep;95-B(9):1239-43. doi: 10.1302/0301-620X.95B9.31717. Oh YM, Eun JP. We investigated the relationship between spinopelvic parameters and disc degeneration in young adult patients with spondylolytic spondylolisthesis. A total of 229 men with a mean age of 21 years (18 to 26) with spondylolytic spondylolisthesis were identified. All radiological measurements, including pelvic incidence, sacral […]

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01 Aug
2013
Disc, Disc Degeneration, Disc Herniation, Musculoskeletal System
By André Broussard, D.C.

Do intervertebral discs degenerate before they herniate, or after? – Full Text Article

The Bone & Joint Journal Vol. 95-B, No. 8 P. Lama, C. L. Le Maitre, P. Dolan, J. F. Tarlton, I. J. Harding, M. A. Adams Published Online:1 Aug 2013 https://doi.org/10.1302/0301-620X.95B8.31660 The belief that an intervertebral disc must degenerate before it can herniate has clinical and medicolegal significance, but lacks scientific validity. We hypothesised that […]

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03 Mar
2013
Disc, Disc Degeneration, Musculoskeletal System
By André Broussard, D.C.

The molecular basis of intervertebral disc degeneration

The Spine Journal Volume 13, Issue 3, March 2013, Pages 318-330 Christopher K.Kepler MD https://doi.org/10.1016/j.spinee.2012.12.003 Abstract Background Intervertebral disc (IVD) degeneration remains a clinically important condition for which treatment is costly and relatively ineffective. The molecular basis of degenerative disc disease has been an intense focus of research recently, which has greatly increased our understanding […]

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22 Jan
2013
Diagnostics, Disc, Disc Bulging, Disc Degeneration, Disc Extrusion, Disc Herniation, Disc Protrusion, MRI, Musculoskeletal System
By André Broussard, D.C.

Clinical correlation of magnetic resonance imaging with symptom complex in prolapsed intervertebral disc disease

J Craniovertebr Junction Spine. 2013 Jan;4(1):16-20. doi: 10.4103/0974-8237.121619. Clinical correlation of magnetic resonance imaging with symptom complex in prolapsed intervertebral disc disease: A cross-sectional double blind analysis. Bajpai J1, Saini S1, Singh R1. Abstract INTRODUCTION: Low backache (LBA) is one of the most common problems and herniated lumbar disc is one of the most commonly […]

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21 Jan
2013
Disc, Disc Degeneration, Disc Herniation, Interleukin-1 beta, Interleukin-6 (IL-6), Interleukin-8 (IL-8), Lumbar Spine & Low Back Pain, Matrix Metalloproteinase, Musculoskeletal System, Sciatica
By André Broussard, D.C.

Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain

Global Spine J 2013; 03(03): 175-184 Karin Wuertz Abstract Although degeneration of the intervertebral disk has historically been described as a misbalance between anabolic and catabolic factors, the role of inflammatory mediators has long been neglected. However, past research clearly indicates that inflammatory mediators such as interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor-α are […]

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25 Jan
2012
Disc, Disc Bulging, Disc Degeneration, Disc Extrusion, Disc Herniation, Disc Prolapse, Disc Protrusion, Inversion Therapy, Lumbar HNP, Lumbar Spine & Low Back Pain, Physical Modalities
By André Broussard, D.C.

Inversion therapy in patients with pure single level lumbar discogenic disease: a pilot randomized trial

Disabil Rehabil. 2012;34(17):1473-80. doi: 10.3109/09638288.2011.647231. Epub 2012 Jan 23. K S Manjunath Prasad Abstract Purpose: Backache and sciatica due to protuberant disc disease is a major cause of lost working days and health expenditure. Surgery is a well-established option in the management flowchart. There is no strong evidence proving that traction for sciatica is effective. […]

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08 Jan
2009
Disc, Disc Degeneration, Lumbar Spine & Low Back Pain
By André Broussard, D.C.

The Twin Spine Study: Contributions to a changing view of disc degeneration

The Spine Journal Volume 9, Issue 1, January 2009, Pages 47-59 Michele C. Battié PhD Abstract Background context Disc degeneration was commonly viewed over much of the last century as a result of aging and “wear and tear” from mechanical insults and injuries. Thus, prevention strategies and research in lumbar degenerative changes and associated clinical […]

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