Disc

Low back pain: A biomechanical rationale based on “patterns” of disc degeneration

Spine (Phila Pa 1976). 2015 May 20. [Epub ahead of print] Von Forell GA1 Stephens TK, Samartzis D, Bowden AE. Abstract STUDY DESIGN: A nonlinear finite element study of a lumbar spine with different “patterns” of multi-level intervertebral disc degeneration. OBJECTIVE: To determine how different patterns of multi-level disc degeneration influence the biomechanical behavior of the […]

Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability

Andrew J Teichtahl Arthritis Research & Therapy 2015, 17:114 doi:10.1186/s13075-015-0629-y The electronic version of this article is the complete one and can be found online at: http://arthritis-research.com/content/17/1/114 Published: 7 May 2015 © 2015 Teichtahl et al.; licensee BioMed Central. Introduction Although physical inactivity has been associated with numerous chronic musculoskeletal complaints, few studies have examined […]

Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability

Arthritis Res Ther. 2015; 17(1): 114. Published online 2015 May 7. doi: 10.1186/s13075-015-0629-y PMCID: PMC4422596 Andrew J Teichtahl, Donna M Urquhart, Yuanyuan Wang, Anita E Wluka, Richard O’Sullivan, Graeme Jones, and Flavia M . Abstract Introduction Although physical inactivity has been associated with numerous chronic musculoskeletal complaints, few studies have examined its associations with spinal […]

Systematic literature review of imaging features of spinal degeneration in asymptomatic populations

AJNR Am J Neuroradiol. 2015 Apr;36(4):811-6. doi: 10.3174/ajnr.A4173. Epub 2014 Nov 27. Brinjikji W Abstract BACKGROUND AND PURPOSE: Degenerative changes are commonly found in spine imaging but often occur in pain-free individuals as well as those with back pain. We sought to estimate the prevalence, by age, of common degenerative spine conditions by performing a […]

The association of combination of disc degeneration, end plate signal change, and Schmorl node with low back pain in a large population study

The Spine Journal Volume 15, Issue 4, 1 April 2015, Pages 622–628 The association of combination of disc degeneration, end plate signal change, and Schmorl node with low back pain in a large population study: the Wakayama Spine Study Masatoshi Teraguchi, MD, PhD Abstract Background context Disc degeneration (DD) reportedly causes low back pain (LBP) […]

Severe disc degeneration is associated with all cause mortality and abdominal aortic calcification assessed prospectively in older men

Arthritis Rheumatol. 2015 Mar 13. doi: 10.1002/art.39055. [Epub ahead of print] Severe disc degeneration is associated with all cause mortality and abdominal aortic calcification assessed prospectively in older men – the MINOS study. Estublier C1, Chapurlat R, Szulc P. Author information Abstract Objective We assessed the association of disc degeneration with all cause mortality and with abdominal aortic […]

Inflammation in intervertebral disc degeneration and regeneration – Full Text Article

Journal of the Royal Society Interface Maria Molinos, Catarina R. Almeida, Joana Caldeira, Carla Cunha, Raquel M. Gonçalves and Mário A. Barbosa Published:06 March 2015 https://doi.org/10.1098/rsif.2014.1191 Abstract Intervertebral disc (IVD) degeneration is one of the major causes of low back pain, a problem with a heavy economic burden, which has been increasing in prevalence as […]

The correlation of radiographic findings and patient symptomatology in cervical degenerative joint disease

The correlation of radiographic findings and patient symptomatology in cervical degenerative joint disease: a cross-sectional study Iris Sun Rudy, Alexandra Poulos, Laura Owen, Ashlee Batters, Kasia Kieliszek, Jessica Willox and Hazel Jenkins Chiropractic & Manual Therapies 2015, 23:9 doi:10.1186/s12998-015-0052-0 Abstract Background There are few known studies investigating the correlation of symptomatology with the specific subtypes of cervical spine […]

NF-κB signaling pathway is a key mediator of disc degeneration

Effects of Nuclear Factor Kappa B Signaling Pathway in Human Intervertebral Disc Degeneration Zhongyi, Sun PhD; Sai, Zhao PhD; Chao, Liu PhD; Jiwei, Tian PhD Spine 15 February 2015 Vol. 40 – Issue 4: p 224–232 Abstract Study Design. IL-1β (interleukin-1β) can activate human nucleus pulposus cells with or without nuclear factor kappa B (NF-κB) […]

Influences of spinal decompression therapy and general traction therapy on the pain, disability, and straight leg raising of patients with intervertebral disc herniation

Journal of Physical Therapy Science Vol. 27 (2015) No. 2 February p. 481-Jioun Choi [Purpose] The purpose of this study was to identify how spinal decompression therapy and general traction therapy influence the pain, disability, and straight leg raise (SLR) ability of patients with intervertebral disc herniation. [Subjects] The subjects were 30 patients with chronic […]

World Federation of Chiropractic – The suggested reading list for chiropractic

The suggested reading list for chiropractic WFC Publishes New Online Reading List Monday January 26, 2015 The World Federation of Chiropractic (WFC) is pleased to announce the debut of an important, online, free service for the chiropractic profession and the public it serves – a Suggested Reading List of key research papers. When you want […]

Symptomatic versus Asymptomatic Intervertebral Disc Degeneration: Is Inflammation the Key?

Critical Reviews™ in Eukaryotic Gene Expression Volume 25, 2015 Issue 1 DOI: 10.1615/CritRevEukaryotGeneExpr.2015012369 pages 13-21 Yan Peng Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong Feng-Juan Lv Department of Orthopaedics and Traumatology, Li Ka Shing Faculty of Medicine, The University of Hong Kong; HKU Shenzhen Institute of […]

Distribution of Schmorl Nodes in the Lumbar Spine and Their Relationship With Lumbar Disk Degeneration and Range of Motion

Yin, Ruofeng MD Spine 01 January 2015 Vol. 40 – Issue 1: p E49–E53 Abstract Study Design. A kinematic magnetic resonance imaging study. Objective. To investigate the distribution of Schmorl nodes (SNs) in the lumbar spine in healthy adults, and determine the association with lumbar disk degeneration and lumbar spine motion. Summary of Background Data. […]

Lumbar Spine Degenerative Disc Disease and Chiropractic Spinal Adjusting Pathophysiology, Safety, Effectiveness

DECEMBER 5, 2014 BY CHIROTRUST Introduction A pioneering study was published inThe New England Journal of Medicinein 1994 (1). Researchers from Hoag Memorial Hospital in Newport Beach, California, performed magnetic resonance imaging (MRI) examinations on 98 people who did not have back pain. Sixty-four percent of the 98 asymptomatic subjects were found to have abnormal […]

The Within-Session Change In Low Back Pain Intensity Following Spinal Manipulative Therapy Is Related To Differences In Diffusion Of Water In The Intervertebral Discs Of The Upper Lumbar Spine And L5-S1

Authors: Paul F. Beattie, PT, PhD, OCS, FAPTA1, Raymond Butts, DPT, PhD2, Jonathan W. Donley, DPT, ATC2, Derek M. Liuzzo, DPT1 Published: Journal of Orthopaedic & Sports Physical Therapy, 2014, Volume: 44 Issue: 1 Pages: 19-29 doi:10.2519/jospt.2014.4967 Study Design Single-group, prospective, repeated-measures design with responder analysis. Objective To determine differences in the changes in diffusion […]

Athletic activity did not increase early disc degeneration or herniation risk in adolescents

October 30, 2014 PHILADELPHIA — Athletic activity did not put adolescents at an increased risk of developing disc degeneration or disc herniation, according to a speaker here. Greg Schroeder, MD, presented the findings of a retrospective, randomized, blinded review at the Philadelphia Spine Research Symposium. Schroeder and colleagues reviewed the medical records of adolescent patients […]

Interrater and intrarater agreements of magnetic resonance imaging findings in the lumbar spine: significant variability across degenerative conditions.

Spine J. 2014 Oct 1;14(10):2442-8. doi: 10.1016/j.spinee.2014.03.010. Epub 2014 Mar 15. Fu MC1, Buerba RA1, Long WD 3rd1, Blizzard DJ2, Lischuk AW3, Haims AH3, Grauer JN4. Abstract BACKGROUND CONTEXT: Magnetic resonance imaging (MRI) is frequently used in the evaluation of degenerative conditions in the lumbar spine. The relative interrater and intrarater agreements of MRI findings […]

Determinants of evolution of endplate and disc degeneration in the lumbar spine: a multifactorial perspective

Eur Spine J. 2014 Sep;23(9):1863-8. doi: 10.1007/s00586-014-3382-z. Epub 2014 Jun 5. Farshad-Amacker NA1, Hughes AP, Aichmair A, Herzog RJ, Farshad M. Abstract PURPOSE: Evolution and progression of disc and endplate bone marrow degeneration of the lumbar spine are thought to be multifactorial, yet, their influence and interactions are not understood. The aim of this study […]

Short-Term Effect of Spinal Manipulation on Pain Perception, Spinal Mobility, and Full Height Recovery in Male Subjects With Degenerative Disk Disease – Full Text

Archives of Physical Medicine and Rehabilitation Volume 95, Issue 9, Pages 1613–1619, September 2014 Felipe Vieira-Pellenz, PT, PhD Abstract Objective To evaluate the short-term effect on spinal mobility, pain perception, neural mechanosensitivity, and full height recovery after high-velocity, low-amplitude (HVLA) spinal manipulation (SM) in the lumbosacral joint (L5-S1). Design Randomized, double-blind, controlled clinical trial with […]

Significance of cartilage endplate within herniated disc tissue

European Spine Journal September 2014, Volume 23, Issue 9, pp 1869-1877 Date: 20 Jun 2014 Significance of cartilage endplate within herniated disc tissue Polly Lama Abstract Purpose Disc herniations sometimes contain hyaline cartilage fragments, but their origins and significance are uncertain. Methods Herniations were removed surgically from 21 patients (aged 35–74 years) whose main symptom […]