Journal of Integrative Medicine Available online 9 May 2019 GilesGyer Abstract Spinal manipulation has been an effective intervention for the management of various musculoskeletal disorders. However, the mechanisms underlying the pain modulatory effects of spinal manipulation remain elusive. Although both biomechanical and neurophysiological phenomena have been thought to play a role in the observed clinical […]
Neural Plasticity Volume 2016, Article ID 3704964, 9 pages http://dx.doi.org/10.1155/2016/3704964 Dina Lelic Received 12 November 2015; Accepted 28 January 2016 Abstract Objectives. Studies have shown decreases in N30 somatosensory evoked potential (SEP) peak amplitudes following spinal manipulation (SM) of dysfunctional segments in subclinical pain (SCP) populations. This study sought to verify these findings and to […]
René Pelletier BMC Musculoskeletal Disorders 2015, 16:25 doi:10.1186/s12891-015-0480-y Abstract Background Musculoskeletal rehabilitative care and research have traditionally been guided by a structural pathology paradigm and directed their resources towards the structural, functional, and biological abnormalities located locally within the musculoskeletal system to understand and treat Musculoskeletal Disorders (MSD). However the structural pathology model does not […]
J Manipulative Physiol Ther. 2014 Oct 2. pii: S0161-4754(14)00171-7. doi: 10.1016/j.jmpt.2014.09.001. [Epub ahead of print] Immediate Changes After Manual Therapy in Resting-State Functional Connectivity as Measured by Functional Magnetic Resonance Imaging in Participants With Induced Low Back Pain. Gay CW1, Robinson ME, George SZ3, Perlstein WM4, Bishop MD5. Abstract OBJECTIVE: The purposes of this study […]
Meier ML,et al. J Manipulative Physiol Ther. 2014 Jan;37(1):32-41. doi: 10.1016/j.jmpt.2013.09.004. Epub 2013 Nov 12. Abstract OBJECTIVE: The purpose of this study was to develop and test a clinically relevant method to mechanically stimulate lumbar functional spinal units while recording brain activity by means of functional magnetic resonance imaging (MRI). METHODS: Subjects were investigated in […]
Citation: Rodriguez-Raecke R, Niemeier A, Ihle K, Ruether W, May A (2013) Structural Brain Changes in Chronic Pain Reflect Probably Neither Damage Nor Atrophy. PLoS ONE 8(2): e54475. doi:10.1371/journal.pone.0054475 Abstract Chronic pain appears to be associated with brain gray matter reduction in areas ascribable to the transmission of pain. The morphological processes underlying these structural […]
Maeda Y, et al. Neuroimage Clin. 2013;2:313-319. PubMed Reference Abstract OBJECTIVE: Carpal tunnel syndrome (CTS) is a common median nerve entrapment neuropathy characterized by pain, paresthesias, diminished peripheral nerve conduction velocity (NCV) and maladaptive functional brain neuroplasticity. We evaluated structural reorganization in brain gray (GM) and white (WM) matter and whether such plasticity is linked […]
JMPT June 2004 Volume 27, Issue 5, Pages 314–326 Robert W Boal, PhD Abstract Objective Recent experimental evidence demonstrating neuronal/synaptic plasticity and, in particular, long-term potentiation (LTP) and long-term depression (LTD) in spinal neurons is reviewed. The implications of these studies for possible mechanistic explanations of low back pain and its remediation by spinal manipulative […]