July 10, 2024 Hepatology (Baltimore, Md.) TAKE-HOME MESSAGE This study assessed the safety and efficacy of treatment with phospholipid curcumin (Meriva®), a phospholipid formulation with ameliorated systemic curcumin absorption and delivery, in patients with NASH. A total of 52 patients with NASH (a majority of whom had fibrosis and chronic kidney disease) were randomized to […]
October 02, 2023 BMJ Evidence-Based Medicine
Journal of Bodywork and Movement Therapies MYOFASCIAL PAIN AND TREATMENT | VOLUME 28, P104-113, OCTOBER 01, 2021 Mythili Kalladka Published: August 07, 2021 DOI:https://doi.org/10.1016/j.jbmt.2021.07.015 Abstract Objectives Temporomandibular disorders (TMDs) are an umbrella term encompassing disorders of both the temporomandibular joint (TMJD) and masticatory musculature (MMD). The objective of this review is to provide an overview […]
October 01, 2020 Annals of Internal Medicine TAKE-HOME MESSAGE This randomized controlled trial examined the use curcumin over 12 weeks for treatment of osteoarthritis. Use of curcumin improved pain for patients, but did not improve effusion volumes or relaxation time of the lateral femoral cartilage when compared with placebo. Curcumin is presented as a potential […]
Medicine (Baltimore). 2020 Jul 10; 99(28): e20373. Published online 2020 Jul 10. doi: 10.1097/MD.0000000000020373 PMCID: PMC7360261 PMID: 32664057 A randomized controlled study Girish H. Rudrappa, MBBS, MS. ORTHO, DNB Abstract Background: Acetaminophen (paracetamol) is one of the most commonly used over-the-counter for pain relief. Management of acute pain with plant-based nutrients has remained suboptimal due […]
Nutr Metab Cardiovasc Dis. 2019 Dec 30. pii: S0939-4753(19)30459-4. doi: 10.1016/j.numecd.2019.12.010. [Epub ahead of print] Kuszewski JC1, Wong RHX2, Wood LG3, Howe PRC4. Author information Abstract BACKGROUND AND AIMS: Chronic conditions such as obesity, which contribute to endothelial dysfunction in older adults, can cause impairments in cerebrovascular perfusion, which is associated with accelerated cognitive decline. […]
J Cell Physiol. 2019 Aug;234(8):12581-12594. doi: 10.1002/jcp.28134. Epub 2019 Jan 13. Dietary natural products as emerging lipoprotein(a)-lowering agents Amir Abbas Momtazi-Borojeni PMID: 30637725 DOI: 10.1002/jcp.28134 Abstract Elevated plasma lipoprotein(a) (Lp(a)) levels are associated with an increased risk of cardiovascular disease (CVD). Hitherto, niacin has been the drug of choice to reduce elevated Lp(a) levels in […]
The Journal of Alternative and Complementary Medicine Vol. 25, No. 6 Original Articles Bradley Leech, Janet Schloss, and Amie Steel Published Online:4 Jun 2019 https://doi.org/10.1089/acm.2018.0374 Abstract Objectives: This study aims to explore the treatment interventions complementary and integrative medicine (CIM) practitioners use in the management of an emerging health condition, increased intestinal permeability (IP), and […]
Phytother Res. 2019 Feb;33(2):253-262. doi: 10.1002/ptr.6226. Epub 2018 Nov 7. Tabrizi R1, Vakili S2, Akbari M1, Mirhosseini N3, Lankarani KB1, Rahimi M4, Mobini M5, Jafarnejad S6, Vahedpoor Z7, Asemi Z6. Abstract Besides other benefits, curcumin is getting more recognized for its antioxidant and anti-inflammatory properties, highlighting the importance of curcumin application for chronic disease prevention. […]
by Gary W. Small, MD Jul 5, 2018 Dr Small is Director, Geriatric Psychiatry, Semel Institute for Neuroscience & Human Behavior, University of California Los Angeles. Previous research suggesting that curcumin, a component of the spice turmeric and curried foods, may protect cognition includes the observation that the prevalence of Alzheimer disease among people in their 70s […]
Newswise | July 10, 2018 Newswise—Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 (DYRK2) at […]
Raveendhara R. Bannuru, MD, PhD Seminars in Arthritis & Rheumatism Published March 9, 2018 Abstract Purpose The unfavorable safety profiles of commonly prescribed knee osteoarthritis (OA) treatments have led clinicians and patients to seek safer alternatives. Research has suggested that curcuminoid and boswellia formulations could moderate key inflammatory pathways that are associated with worsening symptoms […]
Metabolism May 2018 Volume 82, Pages 22–35 Jessica J.A. Ferguson Abstract Background Dietary phytosterols (PS) are well-known hypocholesterolaemic agents. Curcumin elicits hypolipidaemic and anti-inflammatory effects in preclinical studies, however, consistent findings in humans are lacking. Objective Concurrent PS and curcumin supplementation may exhibit enhanced hypocholesterolaemic and anti-inflammatory effects to optimise cardio-protection. The objective of this […]
Twice-daily supplements boosted cognitive power over 18 months Date: January 23, 2018 Source: University of California – Los Angeles Summary: Daily consumption of a certain form of curcumin — the substance that gives Indian curry its bright color — improved memory and mood in people with mild, age-related memory loss. Lovers of Indian food, give […]
November 10, 2014 Written by Emiliano Antiga MD, PhD Psoriasis is a common chronic inflammatory disease of the skin, nails, and joints that affects about 2% of the general population, with a significant impact on long-term quality of life. The potential organ toxicity with chronic use of systemic drugs, their immunosuppressive effects with the increased […]
Efficacy and safety of turmeric and curcumin in lowering blood lipid levels in patients with cardiovascular risk factors: A meta-analysis of randomized controlled trials Nutrition Journal | October 13, 2017 Qin S, et al. – This study appraised turmeric and curcumin with respect to efficacy and safety in lowering blood lipids in patients at risk […]
Michael Jurgelewicz, DC, DACBN, DCBCN, CNS There are only a few natural products that have demonstrated such a wide range of protective properties as curcumin. Turmeric has three main bioactive components, namely curcumin, desmethoxycurcumin and bisdemethoxycurcumin. These curcuminoids have many biological effects including anti-inflammatory, antioxidant, antitumor, antibacterial, and antiviral properties. According to a new study […]
– Reduced knee pain, improved quality of life versus placebo; less so than ibuprofen FRIDAY, May 26, 2017 (HealthDay News) — Curcuminoids seem beneficial for knee osteoarthritis (OA), although they are less effective for pain relief than ibuprofen, according to a review and meta-analysis published online May 4 in the International Journal of Rheumatic Diseases. Igho […]