Journal of Bodywork and Movement Therapies MYOFASCIAL PAIN AND TREATMENT | VOLUME 28, P104-113, OCTOBER 01, 2021 Mythili Kalladka Published: August 07, 2021 DOI:https://doi.org/10.1016/j.jbmt.2021.07.015 Abstract Objectives Temporomandibular disorders (TMDs) are an umbrella term encompassing disorders of both the temporomandibular joint (TMJD) and masticatory musculature (MMD). The objective of this review is to provide an overview […]
BMJ — Ma H, et al. | May 17, 2019 In order to evaluate the relation between the risk of cardiovascular disease (CVD) events and habitual glucosamine use, researchers conducted a study involving 466,039 participants free from CVD at baseline who completed a questionnaire on supplement use, including glucosamine. The participants were followed up for […]
Semin Arthritis Rheum. 2016 Feb;45(4 Suppl):S12-7. doi: 10.1016/j.semarthrit.2015.11.011. Epub 2015 Dec 2. Bruyère O, Altman RD, Reginster JY. Abstract The European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ESCEO) treatment algorithm recommends chronic symptomatic slow-acting drugs for osteoarthritis (SYSADOAs) including glucosamine sulfate (GS) and chondroitin sulfate (CS) as first-line therapy for knee […]
By Carolyn Crist August 11, 2017 (Reuters Health) – Oral glucosamine has no more effect than placebo on joint pain, according to a new meta-analysis. The analysis of randomized controlled trials from which data have been made public found that at both three-month and 24-month follow-up points, the supplement had no effect on either hip or knee […]
Michael Jurgelewicz, DC, DACBN, DCBCN Psoriasis is an inflammatory skin condition that is characterized by itchy, scaly skin plaques. The exact cause of psoriasis is unknown; however, more and more evidence suggests that the immune system can be a culprit when it is chronically stimulated, causing an overproduction of cytokines, which maintains an inflammatory environment. […]
What’s the Bottom Line? How much do we know about glucosamine and chondroitin supplements? We have some information about the safety and usefulness of glucosamine and chondroitin from large, high-quality studies in people. What do we know about the effectiveness of glucosamine and chondroitin supplements? Research results suggest that chondroitin isn’t helpful for pain from osteoarthritis of the knee […]
Published: Nov 12, 2014 By Pauline Anderson , Contributing Writer, MedPage Today Taking glucosamine and chondroitin, two popular dietary supplements, doesn’t significantly relieve the pain and stiffness associated with knee osteoarthritis (OA) or modify disease progression, a new study found. After adjusting for potential confounders, subjects who reported using glucosamine/chondroitin at three annual assessments had […]
August 14, 2014 Clinical Rheumatology TAKE-HOME MESSAGE This study examined the efficacy and safety of chondroitin sulfate (CS) capsules administered with glucosamine sulfate (GS) capsules or sachet preparations of glucosamine hydrochloride (GH) for patients with knee osteoarthritis. In total, 1120 patients were randomized 1:1:1 to receive GS and CS capsules three times daily, GH/CS sachet […]
Calamia V, et al. Journal Sci Rep. 2014 Jun 10;4:5069. doi: 10.1038/srep05069. Affiliation Abstract Osteoarthritis (OA) is the most common age-related rheumatic disease. Chondrocytes play a primary role in mediating cartilage destruction and extracellular matrix (ECM) breakdown, which are main features of the OA joint. Quantitative proteomics technologies are demonstrating a very interesting power for studying […]
Associations Between Glucosamine and Chondroitin Supplement Use and Biomarkers of Systemic Inflammation To cite this article: KantorElizabeth D., LampeJohanna W., NavarroSandi L., SongXiaoling, MilneGinger L., and WhiteEmily. The Journal of Alternative and Complementary Medicine. June 2014, 20(6): 479-485. doi:10.1089/acm.2013.0323. Published in Volume: 20 Issue 6: June 10, 2014 Journal Reference ABSTRACT Objectives: Glucosamine and chondroitin […]
March 11, 2014 by Monte Morin A daily glucosamine drink supplement failed to prevent deterioration of knee cartilage, reduce bone bruises or ease knee pain, according to a recent short-term study of the popular, if controversial, dietary product. In a paper published Tuesday in the journal Arthritis & Rheumatology, authors studied the effects of glucosamine […]
A double-blind randomised placebo-controlled clinical trial evaluating single and combination regimens Fransen M,et al. Ann Rheum Dis. 2014 Jan 6. doi: 10.1136/annrheumdis-2013-203954. [Epub ahead of print] Abstract OBJECTIVE: To determine if the dietary supplements, glucosamine and/or chondroitin, result in reduced joint space narrowing (JSN) and pain among people with symptomatic knee osteoarthritis. METHODS: A double-blind […]
September 11, 2013 The American Academy of Orthopaedic Surgeons has released a list of commonly ordered tests or procedures that may not always be necessary in orthopedics as part of ABIM Foundation’s Choose Wisely campaign. “More than one in four Americans require medical attention due to a musculoskeletal condition and that number continues to grow,” Joshua […]
Laurie Barclay, MD May 24, 2013 Glucosamine supplementation was linked to significant, reversible increases in intraocular pressure (IOP) in a small, retrospective study published online May 23 in JAMA Ophthalmology. However, the investigators, led by Ryan K. Murphy, DO, from the University of New England College of Osteopathic Medicine, Biddeford, Maine, and colleagues, could not exclude the potential […]
Jacobs, Lloydine MD Spine: 20 May 2013 – Volume 38 – Issue 12 – p 984–990 Abstract Study Design. Laboratory based controlled in vivo study. Objective. To determine the in vivo effects of oral glucosamine sulfate on intervertebral disc degeneration. Summary of Background Data. Although glucosamine has demonstrated beneficial effect in articular cartilage, clinical benefit […]
In addition, glycosaminoglycan synthesis stimulated by glucosamine provides a possible promising clinical role for treating disc degenerative disorders.
Lucio C. Rovati, MD, Federica Girolami, PharmD, Stefano Persiani, PhD Ther Adv Musculoskel Dis. 2012;4(3):167-180. Abstract Glucosamine is an amino monosaccharide and a natural constituent of glycosaminoglycans in articular cartilage. When administered exogenously, it is used for the treatment of osteoarthritis as a prescription drug or a dietary supplement. The latter use is mainly supported […]