Investigators find something fishy with classical evidence for dietary fish recommendation Oily fish are currently recommended as part of a heart healthy diet. This guideline is partially based on the landmark 1970s study from Bang and Dyerberg that connected the low incidence of coronary artery disease (CAD) among the Eskimos of Greenland to their diet, […]
Review · April 26, 2014 TAKE-HOME MESSAGE This review assessed studies on nutritional supplement use in patients with psoriasis. There was moderate evidence of benefit with fish oil supplementation; however, studies on vitamin D, vitamin B12, and selenium had inconsistent results. The authors conclude that further evaluation by large, randomized trials is needed to determine […]
Detection and treatment of long-chain omega-3 fatty acid deficiency in adolescents with SSRI-resistant major depressive disorder Robert K. McNamara PharmaNutrition Volume 2, Issue 2, April 2014, Pages 38–46 Highlights • SSRI-resistant adolescent MDD patients exhibit robust erythrocyte long-chain omega-3 (LCn−3) fatty acid deficits. • Fish oil supplementation significantly increases erythrocyte LCn−3 fatty acid levels in […]
American Journal of Clinical Nutrition, 04/03/2014 Clinical Article Full Story PubMed Reference Journal Reference Astrup A – Dairy products contribute important nutrients to the diet, including energy, calcium, protein, and other micro– and macronutrients. However, dairy products can be high in saturated fats, and dietary guidelines generally recommend reducing the intake of saturated fatty acids (SFAs) to […]
Fatty acids and consequently diet play an essential role in the formation of inflammatory mediators involved in the pathogenesis of asthma. Because intake variations of omega–6 (n–6) and omega–3 (n–3) fatty acids ultimately determine cell membrane incorporation, changes in diet have the potential to modify downstream production of inflammatory mediators derived from these compounds. It […]
18 MARCH 2014 Rajiv Chowdhury, MD, PhD Abstract Background:Guidelines advocate changes in fatty acid consumption to promote cardiovascular health. Purpose:To summarize evidence about associations between fatty acids and coronary disease. Data Sources:MEDLINE, Science Citation Index, and Cochrane Central Register of Controlled Trials through July 2013. Study Selection:Prospective, observational studies and randomized, controlled trials. Data Extraction:Investigators […]
Research · March 17, 2014 Full Story Journal Reference TAKE-HOME MESSAGE In a randomized clinical trial of 4203 patients between the ages of 50 and 85 years with intermediate/advanced age-related macular degeneration in one eye, daily supplementation with ω-3 fatty acids and lutein + zeaxanthin did not reduce the risk of cardiovascular disease (CVD) or secondary CVD […]
Xue-Yuan Guo, MD Heart, Lung and Circulation Available online 12 March 2014 Background The effects of omega-3 polyunsaturated fatty acids (PUFA) on the prevention of postoperative atrial fibrillation (POAF) are inconclusive in current studies. Moreover, the most appropriate composition of PUFA to play the protective role is unclear. The aim of this meta-analysis was to […]
The objective was to evaluate whether intake of long–chain ω–3 fatty acids from diet and supplements is associated with cause–specific and total mortality. The results suggest that intake of long–chain ω–3 fatty acids may reduce risk of total and cancer–specific mortality. Methods Study participants (n = 70,495) were members of a cohort study (the Vitamins […]
A meta-analysis of randomized controlled trials BMC Public Health Zhang YF, et al. – Omega–3 fatty acids are known to prevent cardiac death. However, previous observational studies have suggested that omega–3 fatty acids are associated with cancer risk in adults. The authors conducted a meta–analysis based on randomized controlled trials to evaluate the effect of […]
Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society Holland S, Silberstein SD, Freitag F, Dodick DW, Argoff C, Ashman E. Evidence-based guideline update: NSAIDs and other complementary treatments for episodic migraine prevention in adults: report of the Quality Standards Subcommittee of the American Academy of Neurology […]
Clin Ophthalmol 2014 Jan 07;2014(8)169-176, A Olenik Research · January 22, 2014 Full Story Journal Reference http://www.dovepress.com/articles.php?article_id=15424 TAKE-HOME MESSAGE This follow-up study to earlier clinical trials evaluated the reports of a large cohort of dry-eye patients regarding improvement in symptoms after adding an oral formulation of omega-3 essential fatty acids and antioxidants to the use of […]
by Mark Hyman, MD Full Story This week’s question is, “I have irritable bowel syndrome. What do I do about it? What causes it? How do I fix my leaky gut? Do I take drugs?” Irritable bowel syndrome is a huge problem that affects almost 50 million Americans or almost one of every six people. […]
Becky McCall January 22, 2014 Full Story A higher level of serum long-chain omega-3 polyunsaturated fatty acids (PUFAs) — an objective biomarker of fish intake — is linked to a lower long-term risk for type 2 diabetes, according to the results of a new prospective, population-based cohort study. Among dietary factors, the long-chain omega-3 PUFAs, […]
Published: Nov 20, 2013 | Updated: Nov 20, 2013 By Charles Bankhead, Staff Writer, MedPage Today Full Story: http://www.medpagetoday.com/HematologyOncology/ProstateCancer/43042 Action Points Prostate cancer patients who consumed a low-fat, high fish oil diet had significantly less tissue inflammation and proliferation as compared with patients who ate a typical Western diet. Note that the study provides support […]
Saturday, 28 December 2013 18:09By John Otrompke, Contributing Writer Better sleep, physical activity, good nutrition and reducing stress and environmental toxins are the keys to reducing chronic pain, especially in women, said Dr. Robert Bonakdar, at the 2nd annual Lifestyle Medicine Summit in Chicago. All too often, though, clinicians focus on the “chief complaint”—the pain itself—and miss opportunities […]
Jonathan Kay, MD December 20, 2013 Hello. I’m Jonathan Kay, Professor of Medicine and Director of Clinical Research in the Division of Rheumatology at UMass Memorial Medical Center and the University of Massachusetts Medical School, both in Worcester, Massachusetts. Welcome to my Medscape blog. Patients often come to my office interested in alternative treatments — […]
Dry Eye Syndrome and Omega-3 Fatty Acid Rahul Bhargava, MD B2/004, Ananda Apartments Sector-48, Noida 201301, India +911204215085 brahul_2371@yahoo.co.in “A Randomized Controlled Trial of Omega-3 Fatty Acids in Dry Eye Syndrome,” Int J Opthalmol, 2013 Dec 18;6(6):811-6. 49814 (3/2014) Kirk Hamilton: Can you share with us your educational background and current position? Rahul Bhargava: I have […]
Interview December 05, 2013 Stuart P Richer OD, PhD Kathy F Freeman OD, FAAO Full Story: http://www.practiceupdate.com/expertopinion/651 Dr. Stuart Richer speaks with Dr. Kathy Freeman of PracticeUpdate about the effects of supplements on the prevention of ocular disease. In Part 1, Dr. Richer discusses the results of the AREDS trials. In Part 2, he goes […]
A dose-response randomized controlled trial Flock MR, Skulas-Ray AC, et al J Am Heart Assoc, 2013 Nov 19; 2(6):e000513. Abstract Background The erythrocyte membrane content of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which constitutes the omega‐3 index (O3I), predicts cardiovascular disease mortality. The amount of EPA+DHA needed to achieve a target O3I is poorly defined, as […]